Results 41 to 50 of about 1,672,319 (284)

A Constitutive Equation for Cyclically Loaded Sands [PDF]

open access: yes, 1981
A rate type constitutive equation with internal parameters is proposed for describing the behaviour of cyclically loaded sands in undrained conditions leading to liquefaction. The mathematical model is checked versus experimental data on undrained cyclic
Szavits-Nossan, A., Kvasnicka, P.
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

The Application of the Functional Variable Method for Solving the Loaded Non-linear Evaluation Equations

open access: yesFrontiers in Applied Mathematics and Statistics, 2022
In this article, we construct exact traveling wave solutions of the loaded Korteweg-de Vries, the loaded modified Korteweg-de Vries, and the loaded Gardner equation by the functional variable method.
Bazar Babajanov, Fakhriddin Abdikarimov
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

A GENERALIZED (G’/G) - EXPANSION METHOD FOR THE LOADED MODIFIED BURGERS–KDV EQUATION

open access: yes, 2022
This paper is dedicated to find the solutions of the equation of the loaded modified Burgers–KdV equation. It is shown to find the solutions via ( / ) G G - expansion method that is one of the most effective way of finding solutions.
Yakubov, H.E   +2 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Efficient chemotherapy of rat glioblastoma using Doxorubicin-loaded PLGA nanoparticles with different stabilizers [PDF]

open access: yes, 2011
Background: Chemotherapy of glioblastoma is largely ineffective as the blood-brain barrier (BBB) prevents entry of most anticancer agents into the brain.
Markus Glatzel   +14 more
core   +2 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

An equation of state for shock loaded powders [PDF]

open access: yesJournal of Applied Physics, 1991
A simple analytical model is developed for the shock Hugoniot of a powdered material. Previous models have exhibited decreasing accuracy when applied to powders and porous materials of high initial porosity. This deficiency has been avoided in the present model.
Petrie, M. W., Page, N. W.
openaire   +4 more sources

On triply coupled vibrations of axially loaded thin-walled composite beams [PDF]

open access: yes, 2010
Free vibration of axially loaded thin-walled composite beams with arbitrary lay-ups is presented. This model is based on the classical lamination theory, and accounts for all the structural coupling coming from material anisotropy.
Lee, Jaehong, Vo, Thuc, Lee, Kihak
core   +1 more source

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