Results 21 to 30 of about 57,572 (258)
Design and Analysis for Hypoid Gears with Ease-Off Flank Modification
Applied Sciences, 2022 An approach of ease-off flank modification for hypoid gears was proposed to improve the meshing performance of automobile drive axle. Firstly, a conjugate pinion matching with gear globally was developed based on gear meshing theory. Secondly, a modified
Qin Wang +5 more
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Jixie chuandong, 2021 In order to study the effect of the symmetry error generated by processing on the herringbone character gear meshing transmission， improve the stability of the transmission， according to the structural characteristics of herringbone gear and gear ...
Weiguo Li +3 more
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Research on Loaded Contact Analysis and Tooth Wear Calculation Method of Cycloid–Pin Gear Reducer
Lubricants, 2023 This study establishes the geometric model of cycloid–pin gear meshing transmission based on the multi-tooth meshing characteristics of the cycloid speed reducer.
Yongqiang Wang +4 more
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Sensitivity Analysis of Helical Gears with Tooth Surface Modification to Applied Torque and Gear Misalignment [PDF]
Xibei Gongye Daxue Xuebao, 2018 The numerical calculation model of time-varying mesh stiffness, static transmission error and composite mesh error of modified helical gears is developed based on loaded tooth contact analysis (LTCA) model.
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Jixie chuandong, 2022 The contact path and transmission error are key indexes for evaluating the meshing performance of spiral bevel gears. The contact path is offset by misalignment，and symmetry and fluctuation amplitude of transmission error change.
Mingkang Wang +4 more
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Multi-condition and Multi-objective Modification Optimization Design of Spur Gear
Jixie chuandong, 2021 Considering that spur gears are used under multiple-condition， the modeling method of modified tooth surface for pinion and the multi-condition and multi-objective modification optimization methods of the spur gear transmission are researched.
Rui Shen, Siwei Yang
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source