Results 111 to 120 of about 1,653,673 (316)

Data Variability in Rheological Measurement of Semi-Solid Foods: Effects of Loading Normal Force

open access: yesApplied Rheology, 2002
Previous studies involving rheological measurement of semi-solid foods have reported a large amount of data variability, but have focused little on understanding the cause of such variability.
Daniels Pearce Melissa J.   +1 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Loading on the Scapho-Trapezium-Trapezoid joint during gripping

open access: yes, 2009
The scapho-trapezium-trapezoid (STT) joint is believed to be highly vulnerable to wear and has been identified clinically as a high risk joint in arthritic patients. A theoretical model [1] of the load transfer through the wrist during gripping, suggests
Stansfield, B.W.   +2 more
core  

Modeling same-direction two-lane traffic for bridge loading

open access: yes, 2011
Many highway bridges carry traffic in two same-direction lanes, and modeling the traffic loading on such bridges has been the subject of numerous studies.
Bernard Enright   +5 more
core   +1 more source

Proposal of a Transport Planning Model for the Removal of Quarry Stone Using a Simulation

open access: yesApplied Sciences
This article describes a transport planning model which applies a simulation to support decision-making in quarry operations. The analysis of the transport system was used as input for creating the model and the subsequent research.
Janka Saderova   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Assessment dynamic ratio for traffic loading on highway bridges

open access: yes, 2011
The determination of characteristic bridge load effect is a complex problem. Usually, statistical extrapolation of simulated static load effects is used to derive a lifetime characteristic static load effect.
O\u27Brien, Eugene J.   +4 more
core   +1 more source

TSUNAMI WAVE LOADING ON A BRIDGE DECK WITH PERFORATIONS [PDF]

open access: yesScience of Tsunami Hazards, 2011
Tsunamis have damaged bridges to various extents in the 2004 Indian Ocean Tsunami. This paper reports an experimental investigation of the effect of perforations in the girders and parapets on the horizontal tsunami loads.
P. Lukkunaprasit   +3 more
doaj  

Home - About - Disclaimer - Privacy