Results 251 to 260 of about 6,457,110 (386)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

A Subject-Specific Surface EMG Model for Estimating L4/L5 Compressive Loading. [PDF]

Bioengineering (Basel)
Dopico PJ, Zucker-Levin A, Singal K, Mihalko WM.   +3 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Polyethylene Stresses in Lumbar Total Joint Replacement Under Elevated Loading: Insights from an Anatomic Finite Element Model. [PDF]

Bioengineering (Basel)
Rundell SA, Spece H, Yarbrough RV, Kurtz SM.   +3 more
europepmc   +1 more source

Vasodilatory Response to Knee Extension with Different Loads

, 2018
Mana KAGITA, Tomoya OBANA, Takayuki Kishi, Eri Kato, Keisuke Yoshida, Akira Shōbo   +5 more
openalex   +2 more sources

Deterioration Modeling of Steel Components in Support of Collapse Prediction of Steel Moment Frames under Earthquake Loading

, 2011
D. Lignos, H. Krawinkler
semanticscholar   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Acoustic emission characteristics and failure precursors under uniaxial cyclic compression. [PDF]

Sci Rep
Zhang Y, Mei F.
europepmc   +1 more source

Prediction of the Dynamic Crack Path of Concrete Under Projectile Impact Loading

Sobhan Pattajoshi, S. Ray
openalex   +1 more source