Results 81 to 90 of about 47,523 (232)

NKX2‐1 Downstream Regulatory Structural Variants Explain a Substantial Proportion of Molecular Diagnoses in Patients With Benign Hereditary Chorea

Movement Disorders, EarlyView.
Abstract Background NKX2‐1–related disorders (NKX2‐1‐RDs) classically present with a triad of neurological, endocrine, and pulmonary manifestations, including benign hereditary chorea. However, in a fraction of patients, NKX2‐1 coding variants are not detected, and variants outside the NKX2‐1 locus have been reported.
Robin Wijngaard, Lucy Dougherty‐de Miguel, German Demidov, Galuh Astuti, Amaia Lasa‐Aranzasti, Ana Cueto‐González, Marta Correa‐Vela, Carlos Lázaro‐Hernández, Charlotte A. Haaxma, Clara D.M. van Karnebeek, David Gómez‐Andrés, Ignacio Iglesias‐Serrano, Jiddeke M. van de Kamp, Jolanda Schieving, Laura Trujillano, Marc Engelen, Beatriz Muñoz‐Cabello, Roderick P.P.W.M. Maas, Thatjana Gardeitchik, Victoria Gonzalez, Annemarie de Vreugd, Cristina Pérez‐Sanchez, Elisabet Lloveras, Erik‐Jan Kamsteeg, Maartje Pennings, Natalia Rey‐Viñets, Javier Sánchez, Ronald van Beek, Antonio Moreno‐Galdó, Lisenka E.L.M. Vissers, Kornelia Neveling, Anna Marcé‐Grau, Machteld M. Oud, Belén Pérez‐Dueñas   +33 more
wiley   +1 more source

Development of Novel mRNA Classifiers to Stratify Preoperative Thyroid Tumor Risk

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Develop a preoperative risk classifier for guiding the extent of surgery in differentiated thyroid carcinomas (DTCs) under 4 cm. Study Design In silico study, validation with retrospective cohort. Setting Genomic data repositories, academic tertiary medical center.
Thomas F. Barrett, Mohamed Jama, Mohammed Alshalalfa, Theresa Tharakan, Yangyang Hao, Joshua P. Klopper, Taylor B. Cavazos, Ryan S. Jackson, Patrik Pipkorn, Jason T. Rich, Paul A. Zolkind, Douglas R. Adkins, Peter Oppelt, Anthony J. Apicelli, Nikhil Rammohan, Taylor C. Brown, Sidharth V. Puram, Sina Jasim, R. Alex Harbison   +18 more
wiley   +1 more source

Hydatid Cyst of Thyroid Gland: A Case Report

Clinical Case Reports
Hydatid cysts in the thyroid gland are extremely rare, even in endemic areas. A 64‐year‐old male presented with a painless swelling on the left side of the thyroid swelling for 2 years.
Prashant Ghimire, Sagar Rana Magar, Bishal Panthi, Prem Bahadur Maharjan, Intjar Khan, Neeraj Thapa, Sujan Paudel, Siddhartha Karn, Prajjwol Luitel   +8 more
doaj   +1 more source

Papillary Thyroid Cancer With Cutaneous Metastasis: A Case Report and Literature Review

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Cutaneous metastasis of papillary thyroid carcinoma is rare, which may present as slowly growing nodules, erythematous papules, or ulcerative nodules. The pathophysiological mechanisms of skin metastasis in thyroid cancer remain unclear.
Yi‐Qing Gao, Xin‐Lu Yin, Lu‐Ying Zheng, Jia‐Dong Wang   +3 more
wiley   +1 more source

Is It Safe to Omit Any Chest X‐Ray Before Removing the Chest Drain After Elective, Non‐Cardiac Thoracic Surgery? A Single‐Center, Retrospective, Case–Control Study

Thoracic Cancer
Background Every patient undergoing non‐cardiac thoracic surgery will receive several chest X‐rays through the perioperative period. The patient might receive a preoperative X‐ray as a baseline as well as several X‐rays before and after drain removal ...
Ioannis Karampinis, Carolin Reker, Laura Grifone, Fabio Souschek, Christian Galata, Davor Stamenovic, Eric Roessner   +6 more
doaj   +1 more source

Clinical Recommendations for Remote Robotic Assisted Surgery From the CRSA 2025 International Consensus Conference

World Journal of Surgery, EarlyView.
Implementation of remote robotic‐assisted surgery (rRAS) has the potential to significantly improve access to high‐quality surgical care for patients worldwide. Advances in robotic systems and telecommunications now enable highly reliable, low latency, and cybersecure connectivity. These technological developments, together with the broader adoption of
Yuman Fong, Dimitri A. Raptis, Louis Kavoussi, Sherry M. Wren, Dennis Fowler, Mehran Anvari, Francesco Bianco, Xiao Liang, Zheyong Li, Xiaoyu Yin, Micaela Piccoli, Saad Aldousari, John Marks, Baiyong Shen, Clifford Ko, Jelle Ruurda, Barbara Seeliger, Jeroen Hagendoorn, Rahila Essani, R. Matthew Walsh, Dmitry Oleynikov, Stephanie B. Jones, Vivek Bindal, Hyun Koo Kim, Woo Jin Hyung, Laleh Melstrom, Daniel Hashimoto, Francesco Celotto, Liaohai Leo Chen, Bryan M. Burt, Kelly Lafaro, Fernando Elli, Yusef Kudsi, Francesca Ratti, Erik Wilson, Paolo Pietro Bianchi, Annette Morgan, Stephen T. Bartlett, Laila Rashidi, Liu Yu, Bill Gawkins, Piet Hinoul, Bill Peine, Yanghee Woo, Mustafa Raoof, Daniel Jones, Supriya Deshpande, Jordana Bernard, Yulun Wang, Dieter C. Broering, Pier Cristoforo Giulianotti   +50 more
wiley   +1 more source

Quantitative Dual‐Energy CT Perfusion Versus SPECT/CT V/Q Scintigraphy for Preoperative Lung Function Assessment: A Prospective Cohort Study

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Introduction Accurate preoperative physiological assessment is critical for high‐risk patients undergoing lung resection to predict postoperative lung function. This study compared quantitative dual‐energy CT (DECT) perfusion with SPECT/CT for lobar perfusion mapping in an at‐risk oncological cohort.
Jack Edward Liu, Kane Nicholls, Audree So, Siddharth M. Kulkarni, Anthony Tu Tran, Stephen A. Barnett, Amy Baker   +6 more
wiley   +1 more source

Clinical Outcomes of the POPCORN Study: Pharmacodynamics of Pre‐Operative PD1 CheckpOint Blockade and Receptor Activator of NF‐κB Ligand (RANKL) Inhibition in Non‐Small Cell Lung Cancer (NSCLC)—A Phase 1B/2 Trial

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Expanding on the growing evidence for neoadjuvant immunotherapy in resectable non‐small cell lung cancer, this study explored neoadjuvant nivolumab ± denosumab. Two of the 10 treated patients achieved a pathological complete response. CD8 T‐cell infiltration correlated with pathological response, warranting ongoing translational research to understand ...
Elizabeth Ahern, Cassie Turner, Rishendran Naidoo, David Godbolt, Amy Ives, Kirsten Popplewell, Zarnie Lwin, Sally Pearson, Kimberley Nelson, Jason Madore, William C Dougall, Brett G. M. Hughes   +11 more
wiley   +1 more source

Measuring patient disability in the peri‐operative period using the WHODAS 2.0 questionnaire: a systematic review

Anaesthesia, EarlyView.
Summary Introduction The World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) is recommended by peri‐operative core outcome sets as a measure of disability. Despite its growing use, the effect of different surgical procedures on disability measured by WHODAS 2.0 remains poorly understood and heterogeneous reporting across studies ...
Romijn M. Boerlage, Daniël van Dartel, Jacqueline E. M. Vernooij, Nick J. Koning, Linda M. Posthuma, Cor J. Kalkman, Carine J. M. Doggen, Benedikt Preckel   +7 more
wiley   +1 more source

Genotype‐directed therapy for non–small cell lung cancer diagnosed during pregnancy: A pooled analysis of seven cases from the Cancer and Pregnancy Registry with maternal and neonatal outcomes and review of the literature

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
In this retrospective case series from a single database of pregnant women with cancer, seven were diagnosed with non‐small cell lung cancer (NSCLC). Chemotherapy and in some cases also biomarker‐directed therapy during pregnancy were associated with disease control allowing delivery closer to term and resulting in improved maternal outcomes compared ...
Reed Firestone, Elyce Cardonick
wiley   +1 more source