Results 111 to 120 of about 23,275,318 (397)
Clinical and Experimental Gastroenterology, 2020 Louise Rasmussen, Hans Jørgen Nielsen, Ib Jarle Christensen Department of Surgical Gastroenterology 360, Hvidovre Hospital, University of Copenhagen, Hvidovre 2650, DenmarkCorrespondence: Louise RasmussenDepartment of Surgical Gastroenterology 360,
Rasmussen L, Nielsen HJ, Christensen IJ
doaj
The implications of breast cancer molecular phenotype for radiation oncology
Frontiers in Oncology, 2011 The identification of distinct molecular subtypes of breast cancer has advanced the understanding and treatment of breast cancer by providing insight into prognosis, patterns of recurrence and effectiveness of therapy.
Shirin eSioshansi +4 more
doaj +1 more source
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
Sheaves and Localization [PDF]
Journal of Algebra, 1996 The purpose of the paper is to calculate projective limits of localization functors. Let \(\sigma\) and \(\tau\) be two idempotent kernel functors in \(R\)-mod. In general \(\sigma\) and \(\tau\) are not necessarily compatible. The author points out that \(\sigma\) and \(\tau\) are compatible iff the canonical sequence of localization functors \(0\to ...
openaire +3 more sources
Local Aggregation in a Dynamic Setting [PDF]
Although it is not possible, in general, to give a macro description of a micro model over the entire state space of the micro model, it is possible to aggregate exactly over a subspace.
Schlicht, Ekkehart
core
Três estratégias para uma mesma experiência estética: em torno do “periférico” na cultura massiva
Rumores, 2010 Este artigo se constitui a partir do estudo dos filmes Cidade de Deus, Gomorra e Distrito 9, buscando apontar três estratégias que servem de base ao processo de passagem, de agenciamento e de reestruturação a que um contexto “local” se expõe na sua ...
Gelson Santana
doaj +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Local limit theorem in deterministic systems [PDF]
, 2019 We show that for every ergodic and aperiodic probability preserving system, there exists a $\mathbb{Z}$ valued, square integrable function $f$ such that the partial sums process of the time series $\left\{f\circ T^i\right\}_{i=0}^\infty$ satisfies the ...
Kosloff, Zemer, Volny, Dalibor
core +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source