Results 121 to 130 of about 9,603,459 (362)

Bridging the Digital Divide: Developing Local Digital Heritage Content and Investigating Localized Digital Solutions

open access: yesLibri
The digital divide, in my view, is not only created due to the lack of local contents but also due to the fact that few digital contents from local sources are found in the digital libraries of higher education in Ethiopia.
Haile Gezae
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Pathogenesis study of blood disease bacterium in local bananas of Malaysia

open access: hybrid, 2023
Jinn Shyuan Ho   +4 more
openalex   +1 more source

Localized emphysema [PDF]

open access: yesActa Radiologica, 1960
S, BRUNNER, O C, POCK-STEEN
openaire   +2 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Local integration: a durable solution for refugees? [PDF]

open access: yesForced Migration Review, 2006
UNHCR supports local integration as one possiblesolution for refugees who cannot return home. Experiencein Mexico, Uganda and Zambia indicates that integrationcan benefi t refugee-hosting communities as well asrefugees.
Ana Low
doaj  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Object recognition from local scale-invariant features

open access: yesProceedings of the Seventh IEEE International Conference on Computer Vision, 1999
D. Lowe
semanticscholar   +1 more source

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