Results 51 to 60 of about 9,163,804 (344)

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Empoderando vidas y naciones resilientes desde el giro biográfico-local

Cercles: revista d'Història Cultural, 2019
Para establecer y fijar los temas y formas de hacer historia, los historiadores debemos estar atentos a la agenda pública global y local. Empowered lives-Resilient nations es el lema de un programa para el desarrollo humano impulsado por la ONU. Mientras
Joseba Agirreazkuenaga
doaj   +1 more source

Proposed Experiment to Test Local Hidden Variable Theories.

, 1969
A theorem of Bell, proving that certain predictions of quantum mechanics are inconsistent with the entire family of local hidden-variable theories, is generalized so as to apply to realizable experiments.
J. Clauser, M. Horne, A. Shimony, R. Holt   +3 more
semanticscholar   +1 more source

A 2.4% DETERMINATION OF THE LOCAL VALUE OF THE HUBBLE CONSTANT [PDF]

, 2016
We use the Wide Field Camera 3 (WFC3) on the Hubble Space Telescope (HST) to reduce the uncertainty in the local value of the Hubble constant from 3.3% to 2.4%.
A. Riess, L. Macri, S. Hoffmann, D. Scolnic, S. Casertano, A. Filippenko, B. Tucker, M. Reid, David O. Jones, J. Silverman, R. Chornock, P. Challis, W. Yuan, P. Brown, R. Foley   +14 more
semanticscholar   +1 more source

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

FEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche, John R. Riordan, Burkhard Tümmler   +2 more
wiley   +1 more source

Local DCPOs, Local CPOs and Local Completions

Electronic Notes in Theoretical Computer Science, 1999
AbstractWe use a subfamily of the Scott-closed sets of a poset to form a local completion of the poset. This is simultaneously a topological analogue of the ideal completion of a poset and a generalization of the sobrification of a topological space. After we show that our construction is the object level of a left adjoint to the forgetful functor from
openaire   +2 more sources

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Identification and Estimation of Local Average Treatment Effects

, 1994
We investigate conditions sufficient for identification of average treatment effects using instrumental variables. First we show that the existence of valid instruments is not sufficient to identify any meaningful average treatment effect.
J. Angrist, G. Imbens
semanticscholar   +1 more source

Incorporating Non-local Information into Information Extraction Systems by Gibbs Sampling

Annual Meeting of the Association for Computational Linguistics, 2005
Most current statistical natural language processing models use only local features so as to permit dynamic programming in inference, but this makes them unable to fully account for the long distance structure that is prevalent in language use.
J. Finkel, Trond Grenager, Christopher D. Manning   +2 more
semanticscholar   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source