Results 31 to 40 of about 3,917,568 (316)

The Efficacy and Safety of Bevacizumab/Irinotecan/Temozolomide (BIT) for Relapsed/Refractory Neuroblastoma: The UK Children's Cancer and Leukaemia Group Experience

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson, Menna Shamma, Upeka Senanayake, Shaimaa Sahmoud, Kathleen Duffin, Victoria Howard, David King, Ayesha Fathani, Blanche Lumb, Andrei Pobischan, Irum Latif Memon, Monzir Ahmed, Rhian Thomas, Gerard Millen, Yasmeen Alomari, Sucheta Vaidya, Lynley V. Marshall, Sally L. George, Ramya Ramanujachar, Juliet Gray, Paola Angelini   +20 more
wiley   +1 more source

Environmental Resource Conflicts and Food Insecurity in Rural Southeast Nigeria: Implications for Humanitarian and Sustainable Development Policies

Journal of Agriculture and Environment for International Development
Environmental resource crises involving farmers and herdsmen in developing nations can affect the realisation of the United Nations 2030 Sustainable Development Goals’(SDGs) targets, such as elimination of poverty, elimination of hunger and food ...
Samuel Okafor, Andrew Ogbochie, Chukwuka Ugwu, Chizoba Oranu, Gloria Amadi, Chigozie Ugwuanyi, Okolo Modesta   +6 more
doaj   +1 more source

Effects of Tissue Pressure on Transgene Expression Characteristics via Renal Local Administration Routes from Ureter or Renal Artery in the Rat Kidney

Pharmaceutics, 2020
We previously developed a renal pressure-mediated transfection method (renal pressure method) as a kidney-specific in vivo gene delivery system. However, additional information on selecting other injection routes and applicable animals remains unclear ...
Natsuko Oyama, Haruyuki Takahashi, Maho Kawaguchi, Hirotaka Miyamoto, Koyo Nishida, Masako Tsurumaru, Mikiro Nakashima, Fumiyoshi Yamashita, Mitsuru Hashida, Shigeru Kawakami   +9 more
doaj   +1 more source

Alveolar Soft Part Sarcoma in Pediatric and Young Adult Patients: A Report From the Children's Oncology Group Study ARST0332

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Alveolar soft part sarcoma (ASPS) is a rare soft tissue sarcoma occurring most commonly in adolescence and young adulthood. Methods We present the clinical characteristics, treatments, and outcomes of patients with newly diagnosed ASPS enrolled on the Children's Oncology Group study ARST0332.
Jacquelyn N. Crane, Wei Xue, Amira Qumseya, Thomas Scharschmidt, Kathryn R. Tringale, Oscar Lopez Nunez, Jiaqi Hu, Donald A. Barkauskas, Rajkumar Venkatramani, Sheri L. Spunt, Aaron R. Weiss, Noah C. Federman   +11 more
wiley   +1 more source

Assessing the Energy Crisis in South Africa: The Socio-Economic Implication and Challenges Ahead [PDF]

E-Journal of Humanities, Arts and Social Sciences
This paper examined the socio-economic implications caused by the current energy crisis South Africa is facing. Although the crisis is not at its worst stage when compared to other countries in Africa, there are still challenges ahead if the crisis at ...
Kazeem Oyedele Lamidi , Lusanda Beauty Juta   +1 more
doaj   +1 more source

SMiT: Local System Administration Across Disparate Environments Utilizing the Cloud [PDF]

, 2013
System administration can be tedious. Most IT departments maintain several (if not several hundred) computers, each of which requires periodic housecleaning: updating of software, clearing of log files, removing old cache files, etc.
Guyot, Kevin
core   +1 more source

Implementing Health‐Related Quality of Life Assessment in Pediatric Oncology: A Feasibility Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background There is growing interest in embedding health‐related quality of life (HRQoL) assessment and patient‐reported outcome measures (PROMs) within clinical cancer care. This study evaluated the feasibility, acceptability, and usability of implementing an electronic PROM (ePROM) platform to measure HRQoL in children with cancer ...
Mikaela Doig, Sophie Jessop, Jordan R. Hansford, Hien Le, Matthew O'Connor, Peter Gorayski, Andrew Cunningham, Amanda Hutchinson, Victoria Bedford, Eva Bezak, Nayana Parange, Kelly Skelton, Timothy Price, Michala Short   +13 more
wiley   +1 more source

The Evolution and Institutionalisation of Business–Government Relations: Public–Private Partnerships in Khon Kaen, Thailand

Journal of Current Southeast Asian Affairs
How does the nature of business–government relations shape the capacity of local governments to accomplish their development objectives? How do different patterns of business–government interaction affect the quantity and quality of public services and ...
Sirisak Laochankham, Peerasit Kamnuansilpa, Allen Hicken   +2 more
doaj   +1 more source

Botulinum toxin for the treatment of lower limb cramp pain in patients with Amyotrophic Lateral Sclerosis [PDF]

, 2020
Background: Muscle cramps and pain associated with them can be seen in patients with amyotrophic lateral sclerosis (ALS) and are known to reduce the quality of life. Pharmacological treatment may not benefit all patients in treating these cramps.
Govindarajan, Raghav, Mehta, Tejas, Sommers, Richard   +2 more
core   +2 more sources

Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano, Alexander Yelak, Walid Kaadan, Shlomo Caduri, Rivka Friedland, Orli Michaeli, Gad Dotan, Osnat Konen   +7 more
wiley   +1 more source