Results 61 to 70 of about 496,747 (294)

The "Majority Illusion" in Social Networks. [PDF]

PLoS ONE, 2016
Individual's decisions, from what product to buy to whether to engage in risky behavior, often depend on the choices, behaviors, or states of other people. People, however, rarely have global knowledge of the states of others, but must estimate them from
Kristina Lerman, Xiaoran Yan, Xin-Zeng Wu   +2 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Local Religion in a Majority-Dominated Society: A Study of Resiliency and Adaptation [PDF]

Pharos Journal of Theology
Local religion adherents in Indonesia, are facing multidimensional challenges amidst majority domination, such as discrimination from the state and non-state actors (communities and religious organizations).
Tri Astutik Haryat, Annisa Mutohharoh
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Non-trivial automata networks do exist that solve the global majority problem with the local majority rule

CoRR
The global majority problem, often referred to as the Density Classification Task, is a classical benchmark in the context of probing the computational capabilities of automata networks. It poses the simple yet challenging problem of determining, by totally local means, whether an arbitrary initial configuration of binary states can evolve to a final ...
Pedro Paulo Balbi, Kévin Perrot, Marius Rolland, Eurico L. P. Ruivo   +3 more
openaire   +2 more sources

Educating a global workforce? [PDF]

, 2007
In the public rhetoric, at least, education is the answer to most, if not all, the questions raised by the global knowledge-based economy. In this chapter we begin an examination of what education promises the global workforce, and what the global ...
Farrell, LE, Farrell, Lesley, Fenwick, Tara, Fenwick, T   +3 more
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Explainable AI for Water Quality Classification Using Ensemble Stacking

Journal of Information Systems and Informatics
This study proposes a robust and interpretable machine learning framework for water quality classification using a publicly available water quality dataset containing 7,996 samples and 20 physicochemical features with an imbalanced class distribution ...
Windha MP Dhuhita, Hastari Utama, Hartatik, Bayu Setiaji, Haryoko   +4 more
doaj   +1 more source