The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang +13 more
wiley +1 more source
Effect of anesthesia type (local or general) on neurocognitive functions in carotid endarterectomy
Ferhat Borulu +5 more
openalex +1 more source
Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao +8 more
wiley +1 more source
A Prospective Evaluation of Opioid Utilization After Upper-Extremity Surgical Procedures: Identifying Consumption Patterns and Determining Prescribing Guidelines. [PDF]
BACKGROUND: Although adequate management of postoperative pain with oral analgesics is an important aspect of surgical procedures, inadvertent overprescribing can lead to excess availability of opioids in the community for potential diversion.
Abboudi, Jack +10 more
core +1 more source
Localized Complications from Local Anesthesia
The inherent safety of local anesthetics allows practitioners to use them frequently with the confidence that adverse events are rare. Nevertheless, complications can occur. The aim of this article is to briefly review the localized adverse events that may result from local anesthetic administration.
openaire +2 more sources
An epi‐intraneural interface is developed through in silico optimization and a novel tridimensional microfabrication pipeline. The device integrates penetrating and epineural contacts on a flexible substrate. Mechanical, electrochemical, and in vivo testing in rat and pig reveal robust implantation, low‐threshold activation, and site‐dependent ...
Federico Ciotti +14 more
wiley +1 more source
The use of tricaine methanesulfonate, clove oil, metomidate, and 2-phenoxyethanol for anesthesia induction in alewives (Alosa pseudoharengus) [PDF]
Anesthetics are widely used in routine aquaculture operations to immobilize animals for tagging, spawning, handling, and vaccination. A number of anesthetics are currently available for finfish, but their efficacy and optimal dosage is highly species ...
Watson, Mark Thomas
core +2 more sources
Editorial Comment to Retropubic tissue fixation system tensioned mini‐sling carried out under local anesthesia cures stress urinary incontinence and intrinsic sphincter deficiency: 1‐year data [PDF]
Chuangyu Qu
openalex +1 more source
Cold Quad‐Modal Nanocomplex for Precise and Quantitative In Vivo Stem Cell Tracking
Multimodal albumin–bismuth sulfide–superparamagnetic iron oxide (ABS) nanocomplexes are developed for stem cell tracking across four different imaging modalities: MRI, MPI, MSOT, and CT. Combining its flexibility with high sensitivity, this quad‐modal imaging agent enables a robust quantification of ABS‐labeled stem cells in vivo.
Ali Shakeri‐Zadeh +4 more
wiley +1 more source
Retrospective analysis of anesthesia for deep brain electrical stimulation in movement disorders
Objective To analyze the merits and demerits, and main points of anesthetic management of different anesthesia regimens for deep brain stimulation (DBS) in movement disorders.
Zhaolong TIAN +3 more
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