Results 241 to 250 of about 296,609 (314)

Surgical Repair of a Partial Penile Amputation From a Hair Tourniquet Under Local Anesthesia. [PDF]

Cureus
Midenberg E, Anele UA.
europepmc   +1 more source

mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling

Advanced Science, EarlyView.
Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim, Huajie Wang, Gao Qianqian, Abdul Waris, Jufang He   +4 more
wiley   +1 more source

Effectiveness of Camouflaged Syringe on Dental Anxiety and Pain During Maxillary Local Anesthesia in Children: A Randomized Controlled Clinical Trial. [PDF]

Int J Dent
Darwish B, Monaqel MBA, Al-Shiekh MN, Karkoutly M.   +3 more
europepmc   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source

Local anesthesia in upper eyelid surgery - Some considerations. [PDF]

Saudi J Ophthalmol
Sharma S, Ambat JM, Kakizaki H.
europepmc   +1 more source

TME/NIR Dual‐Responsive Zinc‐Based Targeted Nanoagonist for Multimodal Amplification of STING‐Mediated Cancer Immunotherapy

Advanced Science, EarlyView.
A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu, Jiawei Wang, Wei Zhang, Zhixuan Wu, Jing Chen, Yujing He, Xiyue Duan, Yaoting He, Xin Xin, Haoyi Xiang, Yijing Wang, Chengwei Wu, Yang Yi, Qing Meng, Yuqian Qiao, Kui Cheng, Xiaojun Long, Zhangfa Song   +17 more
wiley   +1 more source

Brachial Plexus Nerve Transfer Under Wide Awake Local Anesthesia No Tourniquet. [PDF]

Plast Reconstr Surg Glob Open
Jerome JTJ.
europepmc   +1 more source

Effect of general anesthesia vs. local anesthesia and collateral status on outcomes in anterior circulation occlusion. [PDF]

Front Neurol
Chen G, Chen R, Gao T, Wang L, Xu H, Yin W, Gao Y, Zhang L, Zhang Y, Xing P, Yang P, Li Z, Zhang Y, Liu J.   +13 more
europepmc   +1 more source