Results 21 to 30 of about 5,460,582 (410)

Advances in the Understanding of Two-Pore Domain TASK Potassium Channels and Their Potential as Therapeutic Targets

Molecules, 2022
TWIK-related acid-sensitive K+ (TASK) channels, including TASK-1, TASK-3, and TASK-5, are important members of the two-pore domain potassium (K2P) channel family. TASK-5 is not functionally expressed in the recombinant system.
Xueming Fan, Yongzhi Lu, Guizhi Du, Jin Liu   +3 more
doaj   +1 more source

Effect of precooling on pain during local anesthesia administration in children: a systematic review

Journal of dental anesthesia and pain medicine, 2020
This study was conducted to determine how precooling reduces the subjective reported pain and objective pain and to evaluate the effectiveness of precooling the injection site before administration of local anesthesia in children.
S. Tirupathi, Srinitya Rajasekhar
semanticscholar   +1 more source

Buffered versus unbuffered local anesthesia for inferior alveolar nerve block injections in children: a systematic review

Journal of dental anesthesia and pain medicine, 2020
Background The present study aimed to evaluate and compare the efficacy of buffered and unbuffered local anesthesia solutions during inferior alveolar nerve block (IANB) administration in children.
S. Tirupathi, Srinitya Rajasekhar
semanticscholar   +1 more source

Multisite chronic pain and the risk of autoimmune diseases: A Mendelian randomization study

Frontiers in Immunology, 2023
BackgroundAccumulating evidence has demonstrated that an association between chronic pain and autoimmune diseases (AIDs). Nevertheless, it is unclear whether these associations refer to a causal relationship. We used a two-sample Mendelian randomization (
Yidan Tang, Yidan Tang, Weizhi Liu, Weizhi Liu, Weishuang Kong, Shuangyi Zhang, Shuangyi Zhang, Tao Zhu, Tao Zhu   +8 more
doaj   +1 more source

Clinical parameters of the local anesthetic effects of bupivacaine applied with and without a vasoconstrictor in oral implantology [PDF]

, 2007
Background/Aim. Bupivacaine (Marcaine®), homologue of mepivacaine, chemically related to lidocaine, is used as a local anesthetic for local infiltration, peripheral nerve block, retrobulbar block, symphathetic block, and caudal and epidural anesthesia ...
Bubalo Marija, Duka Miloš, Lazić Zoran, Stamatović Novak, Tatić Zoran, Veljović Milić   +5 more
core   +1 more source

Effect of warming local anesthesia solutions before intraoral administration in dentistry: a systematic review

Journal of dental anesthesia and pain medicine, 2020
Background The aim of the present systematic review was to evaluate and compare the efficacy of warmed and unwarmed local anesthesia solutions in reduction of pain during intraoral injection administration.
S. Tirupathi, Srinitya Rajasekhar
semanticscholar   +1 more source

Enhanced Antitumor Activity of Lidocaine Nanoparticles Encapsulated by a Self-Assembling Peptide

Frontiers in Pharmacology, 2022
Although local anesthetics (LAs) such as lidocaine have been traditionally used for pain relief, their antitumor activity has attracted more and more attentions in recent years.
Yang Yang, Yang Yang, Jiaxiao Sun, Fei Peng, Fei Peng, Haibei Liu, Haibei Liu, Guoyan Zhao, Guoyan Zhao, Junjie Chen, Wensheng Zhang, Wensheng Zhang, Feng Qiu, Feng Qiu   +13 more
doaj   +1 more source

A Comparison of Spinal Anesthesia Versus Monitored Anesthesia Care With Local Anesthesia in Minimally Invasive Fetal Surgery

Anesthesia and Analgesia, 2020
BACKGROUND: Minimally invasive fetal surgery is commonly performed to treat twin-to-twin transfusion syndrome with selective fetoscopic laser photocoagulation and twin-reversed arterial perfusion sequence using radiofrequency ablation.
M. Ferschl, J. Feiner, Lan T. Vu, Devon Smith, M. Rollins   +4 more
semanticscholar   +1 more source

Tумесцентната техника како регионална анестезија [PDF]

, 2020
Тумесцентната техника е техника на инфилтрација во супкутаното ткиво на голем волумен пуфериранфизиолошки раствор во кој е потопена мала концентрација лидокаин заедно со адреналин.
Nikodinovska-Vasilevska, Violeta, Stevkovska, Mare   +1 more
core   +2 more sources

Role of Virtual Reality in Pain Perception of Patients Following the Administration of Local Anesthesia

Annals of Maxillofacial Surgery, 2019
Background: Dental anxiety and anxiety-related avoidance of dental care creates significant problems for the patients and dental practitioners. Administration of local anesthesia is one of the procedures which results in increased anxiety level among ...
VR Sweta, RP Abhinav, A. Ramesh
semanticscholar   +1 more source