Results 21 to 30 of about 5,332,407 (361)
Frontiers in Microbiology, 2023 BackgroundPrevious studies have implicated a vital association between gut microbiota/gut microbial metabolites and low back pain (LBP), but their causal relationship is still unclear.
Mengchan Su +8 more
doaj +1 more source
Development of Lidocaine-Loaded Dissolving Microneedle for Rapid and Efficient Local Anesthesia
Pharmaceutics, 2020 Lidocaine is a local anesthetic agent used in the form of injection and topical cream. However, these formulation types have limitations of being either painful or slow-acting, thereby hindering effective and complete clinical performance of lidocaine ...
Huisuk Yang +12 more
semanticscholar +1 more source
Multisite chronic pain and the risk of autoimmune diseases: A Mendelian randomization study
Frontiers in Immunology, 2023 BackgroundAccumulating evidence has demonstrated that an association between chronic pain and autoimmune diseases (AIDs). Nevertheless, it is unclear whether these associations refer to a causal relationship. We used a two-sample Mendelian randomization (
Yidan Tang +8 more
doaj +1 more source
Effect of precooling on pain during local anesthesia administration in children: a systematic review
Journal of dental anesthesia and pain medicine, 2020 This study was conducted to determine how precooling reduces the subjective reported pain and objective pain and to evaluate the effectiveness of precooling the injection site before administration of local anesthesia in children.
S. Tirupathi, Srinitya Rajasekhar
semanticscholar +1 more source
Enhanced Antitumor Activity of Lidocaine Nanoparticles Encapsulated by a Self-Assembling Peptide
Frontiers in Pharmacology, 2022 Although local anesthetics (LAs) such as lidocaine have been traditionally used for pain relief, their antitumor activity has attracted more and more attentions in recent years.
Yang Yang +13 more
doaj +1 more source
Anesthesia and Analgesia, 2020 BACKGROUND: Minimally invasive fetal surgery is commonly performed to treat twin-to-twin transfusion syndrome with selective fetoscopic laser photocoagulation and twin-reversed arterial perfusion sequence using radiofrequency ablation.
M. Ferschl +4 more
semanticscholar +1 more source
Journal of dental anesthesia and pain medicine, 2020 Background The aim of the present systematic review was to evaluate and compare the efficacy of warmed and unwarmed local anesthesia solutions in reduction of pain during intraoral injection administration.
S. Tirupathi, Srinitya Rajasekhar
semanticscholar +1 more source
Effects of Perioperative Epidural Analgesia on Cancer Recurrence and Survival
Frontiers in Oncology, 2022 Surgical resection is the main curative avenue for various cancers. Unfortunately, cancer recurrence following surgery is commonly seen, and typically results in refractory disease and death.
Donghang Zhang +7 more
doaj +1 more source
Brain Sciences, 2023 Astrocytes are morphologically intricate cells and actively modulate the function of the brain. Through numerous fine processes, astrocytes come into contact with neurons, blood vessels, and other glia cells.
Qingran Li +8 more
doaj +1 more source
Pharmacokinetic/Pharmacodynamic Anesthesia Model Incorporating psi-Caputo Fractional Derivatives [PDF]
Computers in Biology and Medicine 167 (2023), Art. 107679, 9 pp, 2023 We present a novel Pharmacokinetic/Pharmacodynamic (PK/PD) model for the induction phase of anesthesia, incorporating the $\psi$-Caputo fractional derivative. By employing the Picard iterative process, we derive a solution for a nonhomogeneous $\psi$-Caputo fractional system to characterize the dynamical behavior of the drugs distribution within a ...
arxiv +1 more source