Results 41 to 50 of about 270,955 (261)

A review on the pharmacology, pharmacokinetics and toxicity of sophocarpine

open access: yesFrontiers in Pharmacology
Sophocarpine is a natural compound that belongs to the quinolizidine alkaloid family, and has a long history of use and widespread distribution in traditional Chinese herbal medicines such as Sophora alopecuroides L., Sophora flavescens Ait., and Sophora
Shichao Wei   +7 more
doaj   +1 more source

Associations of Sleep and Shift Work with Osteoarthritis Risk

open access: yesArthritis Care &Research, Accepted Article.
Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships between circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000‐person cohort, we evaluated associations between sleep duration, sleeplessness/insomnia, and ...
Elizabeth L. Yanik   +5 more
wiley   +1 more source

Causality of genetically determined glucosamine supplementation on cognition and sarcopenia: a Mendelian randomization study

open access: yesFrontiers in Endocrinology
BackgroundEvidence indicates a negative link between glucosamine and age-related cognitive decline and sarcopenia. However, the causal relationship remains uncertain.
Yi Kang   +8 more
doaj   +1 more source

Does Long‐Term Lower Extremity Strength Training in Adults With Knee Osteoarthritis and Varus Alignment Reduce Knee Joint Loading During Gait?

open access: yesArthritis Care &Research, EarlyView.
Objective We examined whether 18 months of strength training in individuals with knee varus alignment and medial tibiofemoral osteoarthritis (OA) reduced knee joint loads during walking compared to an attention control group. Methods This study was a secondary analysis of a randomized clinical trial that compared the effects of strength training to a ...
Stephen P. Messier   +12 more
wiley   +1 more source

Carotid Endarterectomy with Local Anesthesia and LMA/General Anesthesia

open access: yesScienceOpen Research, 2014
There is no clear consensus as to the appropriate anesthetic technique for patients undergoing a carotid endarterectomy. Such patients may have comorbid conditions, such as coronary artery disease, hyperlipidemia, and others.
Hani Annabi   +5 more
doaj   +1 more source

Prevalence of Systemic Lupus Erythematosus in Australia, 2010–2022: A Population‐Based Study Using Linked National Administrative Health Data

open access: yesArthritis Care &Research, Accepted Article.
Objectives Systemic lupus erythematosus (SLE) is a heterogenous inflammatory condition, with widely varying global prevalence estimates. Frequency of SLE in the general population of Australia has been reported to be notably lower than contemporary estimates in countries such as the US or UK at 19‐39 per 100,000 as opposed to 65‐97 per 100,000.
Lucinda Roper   +7 more
wiley   +1 more source

Minimal important change and minimal clinically important difference in pain and function with exercise in hip osteoarthritis

open access: yesArthritis Care &Research, Accepted Article.
Objective The objective of this study was to estimate the minimal important change (MIC) and minimal clinically important difference (MCID) for pain and physical function in individuals with hip osteoarthritis (OA) following a physiotherapist‐guided exercise intervention.
Yareni Guerrero   +8 more
wiley   +1 more source

Formal and informal social care in people with Rheumatic and Musculoskeletal diseases: a cross‐sectional multicentre survey

open access: yesArthritis Care &Research, Accepted Article.
Introduction Rheumatic and musculoskeletal diseases(RMDs) are leading causes of physical disability, necessitating support with activities of daily living(ADLs). This study describes social care received by patients with RMDs in two disperate regions of England: Salford(urban) and Norfolk(rural).
Mehreen Somro   +6 more
wiley   +1 more source

Phentolamine mesylate: It′s role as a reversal agent for unwarranted prolonged local analgesia

open access: yesJournal of Indian Society of Pedodontics and Preventive Dentistry, 2015
Administration of local anesthesia is an integral procedure prior to dental treatments to minimize the associated pain. It is learned that its effect stays more than the time required for the dental procedure to be completed.
Harpreet Singh Grover   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy