Results 71 to 80 of about 295,501 (266)
Acta Cirúrgica Brasileira, 2008 PURPOSE: To compare the hemodynamic repercussions following a toxic dose of levobupivacaine and bupivacaine intravascularly injected in swines. Methods: Large White pigs were anesthetized with thiopental, tracheal intubation was performed and mechanical ...
Artur Udelsmann +5 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective JAK inhibitors (JAKi) have shown promising effects in early‐phase studies of systemic sclerosis (SSc). We aimed to assess the safety and explore the effectiveness of JAKi compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the European Scleroderma Trials and Research Group (EUSTAR) cohort was ...
Stefano Di Donato +27 more
wiley +1 more source
Arthritis Care &Research, Accepted Article.Objective For cartilage morphology to serve as a scalable endpoint in clinical trials, analyses should be performed automatically without human interaction. To clinically validate artificial intelligence (AI)‐based analysis, we studied cartilage loss from MRI prior to knee replacement.
Felix Eckstein +3 more
wiley +1 more source
Nature CommunicationsDelta opioid receptor (δOR) plays a pivotal role in modulating human sensation and emotion. It is an attractive target for drug discovery since, unlike Mu opioid receptor, it is associated with low risk of drug dependence.
Lin Cheng +17 more
doaj +1 more source
Frontiers in Veterinary ScienceIn the perioperative management of emergency animals, anesthetic drug–related toxicity and adverse effects pose substantial risks, and real-time quantification of anesthetic drug concentrations may provide an effective strategy for improving anesthetic ...
Xiaoyu Xie +5 more
doaj +1 more source
Journal of the American Medical Association, 1908 Except for strictly minor operations, the use of local anesthesia in America is limited to a few clinics, though its adoption abroad is far more general. This limitation may be due, in part, to American hurry, but more probably to inexperience in the method and a certain deeprooted fear of poisoning, traceable to the days of strong cocain solutions ...
openaire +1 more source
Arthritis Care &Research, EarlyView.Interstitial lung disease (ILD) is a significant cause of morbidity and mortality in patients with inflammatory rheumatic disorders (IRDs). High‐resolution computed tomography (HRCT) is widely considered the gold standard for the noninvasive assessment of ILD; however, its interpretation is constrained by substantial interobserver variability and the ...
Alexander Pfeil +7 more
wiley +1 more source
Revista Brasileira de Anestesiologia, 2009 JUSTIFICATIVA E OBJETIVOS: A ropivacaína apresentada na forma levógira pura foi introduzida para proporcionar alternativa mais segura que a bupivacaína nas anestesias locorregionais. O objetivo deste estudo foi comparar as repercussões hemodinâmicas após
Marcos De Simone Melo +3 more
doaj +1 more source
Clinical Characteristics and Concordance of Anti‐MDA5 Antibodies: A Multicenter Australian Study
Arthritis Care &Research, EarlyView.Objective In Australia, anti‐MDA5 antibodies are exclusively tested by a line immunoblot assay (LIA). The clinical concordance of an LIA‐positive anti‐MDA5 result is unclear. We aimed to describe the clinical features and determine the clinical concordance of patients with anti‐MDA5 antibodies. Methods Electronic records of a multisite cohort (patients
Syed B. Ali +11 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective To assess the validity of the Patient‐Reported Outcomes Measurement Information System (PROMIS) Pediatric measures in patients with chronic nonbacterial osteomyelitis (CNO). Methods Within the longitudinal patient registry of CNO, English‐speaking patients aged 8 years and older self‐reported PROMIS Pediatric measures of fatigue, pain ...
Mary M. Eckert +43 more
wiley +1 more source