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Local Anesthetics: Eutectic Mixture of Local Anesthetics
1991All commonly available local anesthetics have poor skin penetration when applied topically. One of the main reasons is that a local anesthetic agent needs to be in its cationic form in order to block nerve conduction. But it is the uncharged base which penetrates and diffuses into the tissues after topical administration.
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Dermatologic Clinics, 1994
Although lidocaine alone will serve as an excellent anesthetic for most patients, using less painful injectable agents, topical anesthetics, and occasionally oral sedation will offer the frightened or pain-intolerant patient an acceptable and effective alternative system of local anesthesia.
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Although lidocaine alone will serve as an excellent anesthetic for most patients, using less painful injectable agents, topical anesthetics, and occasionally oral sedation will offer the frightened or pain-intolerant patient an acceptable and effective alternative system of local anesthesia.
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THE PHARMACOLOGY OF LOCAL ANESTHETICS
Anesthesiology Clinics of North America, 2000The pharmacology of local anesthetics is an integration of the basic physiology of excitable cells and the mechanism by which local anesthetics are capable of interrupting conduction of neural messages. The common characteristics of the molecules with local anesthetic action have been identified and can explain the properties of the agents.
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Narcotics and Local Anesthetics
Veterinary Clinics of North America: Equine Practice, 1993The recognition and alleviation of animal pain is a growing veterinary and public concern. Pain can be of an acute or chronic nature with different behavioral manifestations. Physiologically, pain is a dynamic and complex phenomenon that produces changes in the central and autonomic nervous systems as well as in the endocrine system.
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Local Anesthetic Toxicity in the Geriatric Population
Drugs & Aging, 2019R. Waldinger, G. Weinberg, M. Gitman
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New England Journal of Medicine, 1976
Local anesthetics comprise one of the most widely used classes of drugs in medicine and dentistry, with their remarkable ability to block, quickly and reversibly, the traffic of impulses through both sensory and motor nerves. Historically, the demonstration of the general anesthetic properties of diethyl ether in 1846 antedated by 38 years Koller's ...
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Local anesthetics comprise one of the most widely used classes of drugs in medicine and dentistry, with their remarkable ability to block, quickly and reversibly, the traffic of impulses through both sensory and motor nerves. Historically, the demonstration of the general anesthetic properties of diethyl ether in 1846 antedated by 38 years Koller's ...
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Local Anesthetic Systemic Toxicity: A Review of Recent Case Reports and Registries
Regional anesthesia and pain medicine, 2017M. Gitman, M. Barrington
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Local anesthetic spread during erector spinae plane block.
Journal of clinical anesthesia, 2018A. De Cassai, T. Tonetti
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