Results 71 to 80 of about 164,126 (358)

Rethinking Strategies for a Pharmaceutical Approach to Pain Related to Connective Tissue–Related Raynaud Phenomenon in the United States

open access: yesArthritis Care &Research, EarlyView.
Objective There are no US Food and Drug Administration–approved therapies for Raynaud phenomenon (RP) in the United States. Clinical trials have been challenged by study design. Important advances in RP patient‐reported outcome measures and mechanistic quantification allow RP‐related pain characterization.
Tracy M. Frech   +4 more
wiley   +1 more source

Evaluating Dental Surgery Post-operative Pain in Children Following Treatment Under General Anesthesia [PDF]

open access: yes, 2011
Purpose: The purpose of this pilot study was to determine if there is a difference in post-operative pain experience for children following dental restorations and/or extractions under general anesthesia (GA), with and without local anesthetic (LA). The
Husson, Malinda
core   +1 more source

Diffusion‐Weighted Imaging for the Evaluation of the Sacroiliac Joint in Pediatric Patients

open access: yesArthritis Care &Research, Accepted Article.
Background Maturational signal in the sacroiliac joint (SIJ) of skeletally immature youth is often misinterpreted as inflammation. Diagnostic tools that improve specificity are greatly needed. Apparent diffusion coefficient (ADC) values from diffusion‐weighted imaging (DWI), when used with standard imaging, may enhance diagnostic accuracy.
Michael L. Francavilla   +6 more
wiley   +1 more source

The use of tricaine methanesulfonate, clove oil, metomidate, and 2-phenoxyethanol for anesthesia induction in alewives (Alosa pseudoharengus) [PDF]

open access: yes, 2015
Anesthetics are widely used in routine aquaculture operations to immobilize animals for tagging, spawning, handling, and vaccination. A number of anesthetics are currently available for finfish, but their efficacy and optimal dosage is highly species ...
Watson, Mark Thomas
core   +2 more sources

The challenge of evaluating pain and a pre-incisional local anesthetic block. [PDF]

open access: yes, 2014
Background. Our objective was to test the effectiveness of a local anesthetic line block administered before surgery in reducing postoperative pain scores in dogs undergoing ovariohysterectomy (OVHX). Methods.
Kass, Philip H   +3 more
core   +2 more sources

β–Cyclodextrin–Propyl Sulfonic Acid Catalysed One-Pot Synthesis of 1,2,4,5-Tetrasubstituted Imidazoles as Local Anesthetic Agents

open access: yesMolecules, 2015
Some functionalized 1,2,4,5-tetrasubstituted imidazole derivatives were synthesized using a one-pot, four component reaction involving 1,2-diketones, aryl aldehydes, ammonium acetate and substituted aromatic amines.
Yan Ran, Ming Li, Zong-Ze Zhang
doaj   +1 more source

Local Anesthetic “Resistance”

open access: yesPain Physician, 2003
The incidence of inadequate analgesia despite technically well performed injections led our clinic to prospectively test patients for response to a variety of local aesthetics. Skin testing was performed on the skin of the forearm away from the site of pathology. Patients were asked to identify "which is the most numb" of the skin wheals. Although most
openaire   +2 more sources

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and One‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

open access: yesArthritis Care &Research, Accepted Article.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension‐phase). During part 1, three doses were assessed in two weight groups (Group A/B: ≥30–60 kg/≥10–<
Fabrizio De Benedetti   +19 more
wiley   +1 more source

Anesthesia in endovascular abdominal aortic aneurysm (AAA) repair [PDF]

open access: yes, 2017
Introduction: endovascular AAA repair can be done using different anesthetic techniques, such as general anesthesia, regional block, and local anesthesia associated with sedation.
Kora, M., Potseluev, V.
core  

NGX-4010, a capsaicin 8% patch, for the treatment of painful HIV-associated distal sensory polyneuropathy: integrated analysis of two phase III, randomized, controlled trials [PDF]

open access: yes, 2013
BACKGROUND HIV-associated distal sensory polyneuropathy (HIV-DSP) is the most frequently reported neurologic complication associated with HIV infection.
Brew, Bruce J   +9 more
core   +1 more source

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