Results 1 to 10 of about 50 (44)
Local anesthetics for the Nephrologist [PDF]
Clinical Kidney Journal, 2021 Abstract Several specialists in medicine use local anesthetics. In patients with kidney disease, these agents are used during catheter insertions for hemodialysis and peritoneal dialysis, arteriovenous fistula and graft procedures, kidney transplantation, parathyroidectomy, kidney biopsies, and dental and skin procedures.
Nupur N Uppal +5 more
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Anais Brasileiros de Dermatologia, 2020 Local anesthetics are essential medications for the conduction of dermatological procedures. They stop the depolarization of nerve fibers and are divided into two main categories, the amide and ester types. Systemic toxicity with reflex on the central nervous and cardiovascular systems is their most feared adverse reactions, and the anaphylactic ...
Ana Carolina Figueiredo Pereira Cherobin +1 more
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Benzonatate as a local anesthetic
PLOS ONE, 2023 Introduction Benzonatate is an FDA-approved antitussive agent that resembles tetracaine, procaine, and cocaine in its chemical structure. Based on structural similarities to known local anesthetics and recent findings of benzonatate exerting local anesthetic-like effects on voltage-gated sodium channels in vitro, we hypothesized that benzonatate will ...
Anna McGuire +4 more
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THE PHARMACOLOGY OF THE LOCAL ANESTHETICS [PDF]
Journal of the American Medical Association, 1919 Acute intoxication in man from the use of the local anesthetics is far more common than is indicated by the number of recorded cases. We undertook to investigate the causes of such intoxication, and sought to find means of avoiding it, or combating it when it arises.
Robert A. Hatcher, Cary Eggleston
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Local anesthetics and their adjuncts [PDF]
Pediatric Anesthesia, 2011 SummaryLocal anesthetics (LA) block propagation of impulses along nerve fibers by inactivation of voltage‐gated sodium channels, which initiate action potentials (1). They act on the cytosolic side of phospholipid membranes. Two main chemical compounds are used, amino esters and amino amides. Amino esters are degraded by pseudocholinesterases in plasma.
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Are Local Anesthetics and General Anesthetics Different? [PDF]
Biophysical Journal, 2014 It is widely believed that general and local anesthetics act by different mechanisms. While there is general agreement that the mode of action of general anesthetics is poorly understood, local anesthetics are believed to block voltage-gated sodium channels and thereby affect action potentials in nerves.
Sasse-Middelhoff, Henrike +2 more
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Journal of the American Medical Association, 1908 Fredonia, N. Y., Aug. 10, 1908. To the Editor: —Allow me to state that at the annual meeting of the Chautauqua County (N. Y.) Medical Society, held July 14, 1896, I reported that: "Quinin is a safe and efficient anesthetic when used hypodermatically and much safer than cocain." A report of the proceedings of that meeting in the Buffalo Medical ...
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Some of the next articles are maybe not open access.
Veterinary Clinics of North America: Large Animal Practice, 1981
Local anesthetics are used in a wide range of clinical situations to prevent acute pain and to stop or ameliorate pain produced by cancer or pain associated with chronic painful conditions. Knowledge of the pharmacology of local anesthetics is essential for their safe use and selection of specific agents to achieve intended goals.Local anesthetics are ...
J. Descotes, J.Cl. Evreux
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Local anesthetics are used in a wide range of clinical situations to prevent acute pain and to stop or ameliorate pain produced by cancer or pain associated with chronic painful conditions. Knowledge of the pharmacology of local anesthetics is essential for their safe use and selection of specific agents to achieve intended goals.Local anesthetics are ...
J. Descotes, J.Cl. Evreux
openaire +4 more sources