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Mechanisms of Cancer Inhibition by Local Anesthetics [PDF]
Frontiers in Pharmacology, 2021 The use of local anesthetics during surgical treatment of cancer patients is an important part of perioperative analgesia. In recent years, it has been showed that local anesthetics can directly or indirectly affect the progression of tumors.
Malay Kishore Dutta +2 more
exaly +4 more sources
Safety of local anesthetics, [PDF]
Anais Brasileiros de Dermatologia, 2020 Local anesthetics are essential medications for the conduction of dermatological procedures. They stop the depolarization of nerve fibers and are divided into two main categories, the amide and ester types.
Ana Carolina Figueiredo Pereira Cherobin +1 more
doaj +6 more sources
Lipid Emulsion for Local Anesthetic Systemic Toxicity [PDF]
Anesthesiology Research and Practice, 2012 The accidental overdose of local anesthetics may prove fatal. The commonly used amide local anesthetics have varying adverse effects on the myocardium, and beyond a certain dose all are capable of causing death.
Sarah Ciechanowicz, Vinod Patil
doaj +3 more sources
Cytotoxicity of Local Anesthetics on Bone, Joint, and Muscle Tissues: A Narrative Review of the Current Literature [PDF]
Journal of Pain Research, 2023 Kaiwen Zhang, Meihong Li, Wenlong Yao, Li Wan Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of ChinaCorrespondence: Li Wan, Department of Anaesthesiology ...
Zhang K, Li M, Yao W, Wan L
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Local anesthetic resistance in a pregnant patient with lumbosacral plexopathy [PDF]
BMC Anesthesiology, 2004 Background We report a case of a patient with apparent resistance to local anesthetics. While similar cases of failure of regional anesthetics are often attributed to technical failure, the overall clinical presentation and history of this patient ...
Ting Paul H, Kavlock Renae
doaj +3 more sources
Quinin as a Local Anesthetic. [PDF]
Journal of the American Medical Association, 1908 Fredonia, N. Y., Aug. 10, 1908. To the Editor: —Allow me to state that at the annual meeting of the Chautauqua County (N. Y.) Medical Society, held July 14, 1896, I reported that: "Quinin is a safe and efficient anesthetic when used hypodermatically and much safer than cocain." A report of the proceedings of that meeting in the Buffalo Medical ...
V. M. Griswold
openalex +3 more sources
Trial watch: local anesthetics in cancer therapy [PDF]
OncoImmunologyPreclinical evidence indicates potent antitumor properties of local anesthetics. Numerous underlying mechanisms explaining such anticancer effects have been identified, suggesting direct cytotoxic as well as indirect immunemediated effects that together ...
Killian Carnet Le Provost +3 more
doaj +2 more sources
Solvent-Driven Enrichment and Multiplex Analysis of Local Anesthetics by Thin-Layer Chromatography Coupled with Surface-Enhanced Raman Spectroscopy [PDF]
MoleculesLocal anesthetics have been widely used in clinical analgesia due to their ability to provide effective regional pain management. Accurate measurement of local anesthetics in body fluids is crucial for ensuring patient medication safety and optimizing ...
Huimin Sui +9 more
doaj +2 more sources
, 2020 The fascinating history of local anesthetics (LAs) began in South America with the herbal and traditional use of cocaine leaves by the indigenous peoples of Peru and Bolivia, the sacred plant of the Incas Erythroxylum coca.
Cárdenas-Maytorena, Ana C. +3 more
core +4 more sources