Results 241 to 250 of about 345,347 (366)

An Agrin–YAP/TAZ Rigidity Sensing Module Drives EGFR‐Addicted Lung Tumorigenesis

open access: yesAdvanced Science, EarlyView.
The study identifies agrin‐EGFR mechanotransduction as a critical driver of lung adenocarcinoma which enhances EGFR signaling through an integrin‐FAK‐actomyosin dependent positive feedback on YAP/TAZ ‐TEAD in response to matrix stiffness. Targeting this oncogenic loop through combinatorial treatments inhibits lung cancer due to agrin impairment.
Reza Bayat Mokhtari   +20 more
wiley   +1 more source

Effect of Dental Local Anesthetics on Reactive Oxygen Species: An In Vitro Study. [PDF]

open access: yesCureus
Kuroda H   +11 more
europepmc   +1 more source

LOCAL ANESTHETICS [PDF]

open access: bronze, 1960
M. A. Bryce-Smith
openalex   +1 more source

Confinement by Liquid‐Liquid Interface Replicates In Vivo Neutrophil Deformations and Elicits Bleb‐Based Migration

open access: yesAdvanced Science, EarlyView.
Leukocytes sense mechanical cues provided by surrounding cells to regulate motility. Replicating the confining pressures applied by soft, elastic tissues in vitro is challenging. Here, the use of liquid‐liquid interfaces is introduced to model forces exerted by surrounding cells. Confining pressures are tunable by controlling interfacial curvature, and
Jonathan H. Schrope   +13 more
wiley   +1 more source

3D‐Printed Biomimetic Vascular Scaffold Crosslinked with Heparan Sulfate for Sustained Release of PDGFB‐LG4 Fusion Protein Promotes Bone Regeneration

open access: yesAdvanced Science, EarlyView.
Fusion protein PDGFB‐LG4 exhibits superior osteoinductive and angiogenic activity compared to PDGFB. The PCLHS‐PDGFB‐LG4 scaffold, featuring perfusable and permeable vascular‐like networks, promotes angiogenesis and osteogenesis through the sustained release of PDGFB‐LG4, thereby accelerating the bone defect repair process.
Jiahua Duan   +6 more
wiley   +1 more source

Immediate-type allergic reactions to local anesthetics

open access: yesAllergology International, 2018
Naomi Nakamura   +3 more
doaj   +1 more source

Knowledge and attitudes toward anaphylaxis to local anesthetics in dental practice. [PDF]

open access: yesBDJ Open
Cherrez-Ojeda I   +8 more
europepmc   +1 more source

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