Results 1 to 10 of about 6,711,395 (246)

Local Antibiotics in the Treatment of Diabetic Foot Infections: A Narrative Review [PDF]

Antibiotics, 2023
Along with the increasing global burden of diabetes, diabetic foot infections (DFI) and diabetic foot osteomyelitis (DFO) remain major challenges for patients and society.
Laura Soldevila-Boixader, Alberto Pérez Fernández, Javier Muñoz Laguna, Ilker Uçkay   +3 more
doaj   +6 more sources

Does the Use of Local Antibiotics Affect Clinical Outcome of Patients with Fracture-Related Infection? [PDF]

Antibiotics, 2022
This international, multi-center study evaluated the effect of antibiotic-loaded carriers (ALCs) on outcome in patients with a fracture-related infection (FRI) and evaluated whether bacterial resistance to the implanted antibiotics influences their ...
Jonathan Sliepen, Ruth A. Corrigan, Maria Dudareva, Marjan Wouthuyzen-Bakker, Rob J. Rentenaar, Bridget L. Atkins, Geertje A. M. Govaert, Martin A. McNally, Frank F. A. IJpma   +8 more
doaj   +2 more sources

Local/Topical Antibiotics for Peri-Implantitis Treatment: A Systematic Review [PDF]

Antibiotics, 2021
Most studies indicate that the mechanical removal of the bacterial biofilm from the implant surface is the central goal of peri-implantitis therapy. However, controversial results in the treatment of peri-implantitis have led to the consideration of ...
Pier Carmine Passarelli, Andrea Netti, Michele Antonio Lopez, Eleonora Favetti Giaquinto, Giuseppe De Rosa, Gianmarco Aureli, Alina Bodnarenko, Piero Papi, Anna Starzyńska, Giorgio Pompa, Antonio D’Addona   +10 more
doaj   +5 more sources

“Anti-Bios”: Can Local Antibiotics Affect Bone Union in Infected Bone Defects Treated with Degradable Bone Substitutes [PDF]

Biomedicines
Background: Segmental bone defects (SBDs) pose significant clinical challenges, often requiring complex reconstructive procedures. Degradable bone substitutes loaded with antibiotics have emerged as promising tools for infection control.
Filippo Vandenbulcke, Salvatore Lorenzo Renne, Giuseppe Anzillotti, Pietro Conte, Giuliano Ravasio, Gabriele Meroni, Federica Riva, Elizaveta Kon   +7 more
doaj   +2 more sources

Comparative Study of Systemic vs. Local Antibiotics with Subgingival Instrumentation in Stage III–IV Periodontitis: A Retrospective Analysis [PDF]

Antibiotics
To improve the clinical and microbiological outcomes of non-surgical mechanical periodontal therapy, the adjunctive use of antimicrobials has been utilized in treating moderate-to-severe periodontitis.
Ioana Ilyes, Marius Boariu, Darian Rusu, Vincenzo Iorio-Siciliano, Octavia Vela, Simina Boia, Viorelia Radulescu, Petra Șurlin, Holger Jentsch, Alexandru Lodin, Stefan-Ioan Stratul   +10 more
doaj   +2 more sources

Mouldable Collagen–Tricalciumphosphate Is a Safe Carrier for Local Antibiotics—Short-Term Results in Revision Hip Arthroplasty [PDF]

Antibiotics
Background: Improving local antibiotic delivery is a promising approach to improve infection control and potentially shorten systemic treatment in periprosthetic joint infection (PJI).
Yannik Hanusrichter, Carsten Gebert, Sven Frieler, Burkhard Moellenbeck, Marcel Dudda, Martin Wessling, Christoph Theil   +6 more
doaj   +2 more sources

A comparison of clinical and radiological outcomes between two different biodegradable local antibiotic carriers used in the single-stage surgical management of long bone osteomyelitis

Bone & Joint Research, 2023
Aims: Dead-space management, following dead bone resection, is an important element of successful chronic osteomyelitis treatment. This study compared two different biodegradable antibiotic carriers used for dead-space management, and reviewed clinical ...
Jamie Ferguson, Jonathan Bourget-Murray, Andrew J. Hotchen, David Stubbs, Martin McNally   +4 more
doaj   +3 more sources

Early periprosthetic infection: dilution, jet dilution or local antibiotics. Which way to go? A meta-analysis on 575 patients [PDF]

GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW, 2020
Objective: Periprosthetic infections (PPI) after total hip and total knee arthroplasty (THA, TKA) are subdivided into early and late infections. Early PPIs are defined as the occurrence of infection within 6 weeks following the primary surgery.
Vees, Tilman, Hofmann, Gunther O.
doaj   +2 more sources

Increase in fracture-related infection in open distal femur fractures treated with locally delivered antibiotics [PDF]

OTA International
. Objectives:. Local antibiotic delivery may reduce fracture-related infections (FRIs), but its efficacy in distal femur fractures remains unclear. This study evaluated (1) usage patterns of local antibiotics in distal femur fractures and (2) their ...
Alexander B. White, MD, Ryan Serbin, MD, Michael Gambuzza, BA, Ziqing Yu, PhD, Rachel B. Seymour, PhD, Meghan K. Wally, PhD, Madhav A. Karunakar, MD, Evidence-Based Musculoskeletal Injury and Trauma Collaborative (EMIT), Aseel Dib, MD, Amber Stanley McKinney, BSPH, Blake Hodgens, MD, Charles Arendale, BS, Calvin Chandler, MD, Luz Chavez-Araujo, BS, Nia Crowley, MS, George Graham, MD, James Frix, MD, Kevin Phelps, MD, Kyara Washington, MPH, Maria Kammire, MD, Madeline Rieker, MD, Robert Mayberry, MD, Susan Odum, PhD, Timothy Yin, BA, William Delk, BS, Joseph R. Hsu, MD, Laurence B. Kempton, MD, Suman Medda, MD, Michael J. Bosse, MD, Stephen H. Sims, MD, Sarah Pierrie, MD, Jack Wiese, BS   +31 more
doaj   +2 more sources

Continuous local antibiotic perfusion: A treatment strategy that allows implant retention in fracture-related infections

Journal of Orthopaedic Surgery, 2022
Purpose Fracture-related infections are difficult to treat because of the formation of biofilms around implants. Systemic antibiotics are notoriously ineffective against biofilms due to their insufficient penetration of tissues with poor vascularity. The
Akihiro Maruo, Takahiro Oda, Ryowa Mineo, Hidetoshi Miya, Hirotsugu Muratsu, Tomoaki Fukui, Keisuke Oe, Ryosuke Kuroda, Takahiro Niikura   +8 more
doaj   +2 more sources