Results 131 to 140 of about 334,763 (303)

Local Authorities Elections (Special Provisions) Bill - Voting Breakdown - Second Reading

open access: yes
This infographic is available in English and published on the Manthri.lk platform which can be accessed from the following link.On February 17, 2025 the second reading of the Local Authorities Elections (Special Provisions) Bill was passed with a ...
Parliamentary Research Team
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Local Government, ‘Race’ and Sports Policy Implementation: Demystifying Equal Opportunities in Local Government.

open access: yes, 2003
This thesis takes as its starting point the position that equal opportunities as a concept and practice have been conceptualised and operationalised inconsistently in local government (Nanton 1989, Young 1990, 1992, Bagilhole 1997).
Hylton, K
core  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Estimating the Costs and Benefits of Local Government Reorganisation: A Case of Korea [PDF]

open access: yes
It appears that few empirical studies have been conducted which are aimed at estimating not only the costs but also the benefits surrounding local government reorganisation, either in academia or in government, and most reports on the issue seem to focus
Young-Chool Choi, Sang-Yeup Lee
core  

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Formative evaluation of community strategies: Process Evaluation of Plan Rationalisation 2004‑2007

open access: yes, 2008
Plan rationalisation is an ongoing process, driven by a broad range of statutory and other changes that are associated with the modernisation of local government. As part of evaluative work on the impact of local government modernisation, Communities and
Monro, Surya
core  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

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