Results 141 to 150 of about 334,763 (303)

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Ensuring effective overview and scrutiny in a re-organised local government system : a case study of the move to unitary status in England

open access: yes
This thesis is a comparative analysis of the impact of local government reorganisation on the overview and scrutiny functions across four unitary local authorities in England. The creation of new unitary authorities in England in 2009 gave an opportunity
Thompson, Philip
core  

Exploring the psychological contract of black British clerical workers in UK local authorities

open access: yes, 2009
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This paper investigates the nature of the psychological contract (PC) of black Brit-ish workers in UK local authorities. Psychological contract describes an
Dadi, Vincent
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Implementing national care guidelines in local authorities in England and Wales: A Theory-of-Change [PDF]

open access: yesBMC Health Serv Res
Bauer A   +7 more
europepmc   +2 more sources

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