Results 161 to 170 of about 334,763 (303)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Public health interventions aimed at children aged 5-19 years funded by local authorities in England: a scoping review of economic analyses. [PDF]

open access: yesBMC Public Health
Golder S   +7 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Baseline assessments of research capacity, capability and culture in UK local authorities: reflections from evaluators embedded in Health Determinants Research Collaborations. [PDF]

open access: yesHealth Res Policy Syst
Bell L   +17 more
europepmc   +2 more sources

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Local authorities and racial disadvantage

open access: yes
SIGLEAvailable from British Library Lending Division - LD:GPB-4598 / BLDSC - British Library Document Supply CentreGBUnited ...
Home Office, London (United Kingdom)
core  

Research for policy Community safety; uses of 1991 census data; housing; local government reorganisation

open access: yes, 1994
SIGLEAvailable from British Library Document Supply Centre-DSC:7755.07603(1994) / BLDSC - British Library Document Supply CentreGBUnited ...
Local Authorities Research and Intelligence Association, London (United Kingdom)   +1 more
core  

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