Results 111 to 120 of about 10,561,922 (303)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Vote Buying In Lampung Local Election

open access: yesMimbar, 2017
Vote buying in elections, both general elections and local elections is a phenomenon in Indonesian politics. Lampung Province has implemented direct elections simultaneously in December 2015 and February 2017.
Robi Cahyadi Kurniawan   +3 more
doaj   +1 more source

Uniform Local Behavior of Stable Subordinators

open access: yesThe Annals of Probability, 1979
Appropriate constant multiples of the function $t^{1/\alpha}$ are "the" "maximal local lower envelope" and "the" "minimal local upper envelope" for the sample functions of a strictly stable subordinator of index $\alpha$. The fact that the probability of extinction of a Galton-Watson process is less than one if the mean number of offspring is larger ...
openaire   +3 more sources

Singular Behavior of Eigenstates in Anderson’s Model of Localization

open access: yesPhysical Review Letters, 2012
We observe a singularity in the electronic properties of the Anderson Model of Localization with bounded diagonal disorder, which is clearly distinct from the well-established mobility edge (localization-delocalization transition) that occurs in dimensions $d>2$. We present results of numerical calculations for Anderson's original (box) distribution
Johri, S., Bhatt, R. N.
openaire   +4 more sources

The local capacity, local community and local governance dimensions of sustainability in Australian Local Government

open access: yes, 2011
The problem of the `financial sustainability of individual local councils represents the most significant policy question at issue in contemporary debate on Australian local government.
Grant, BJ, Dollery, B, Crase, L
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Big Local Partnership Member Surveys, 2016-2024

open access: yes
copyright UK Data Service and data collection copyright owner.Big Local is a long-term, place-based funding programme in England aimed at empowering residents in selected communities to lead local change, build community capacity, and improve outcomes ...
Local Trust
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Health and Social Care Integration: Insights from International Implementation Cases

open access: yesJournal of Market Access & Health Policy
The integration of health and social care is increasingly recognized as essential to address population ageing, the rise in chronic diseases, and persistent health inequities.
Ricardo Correia de Matos   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy