Results 171 to 180 of about 169,388 (257)

Sex as a biological variable in nonclinical studies: Bridging scientific rigor, animal welfare, and regulatory expectations

Animal Models and Experimental Medicine, EarlyView.
Sex as a biological variable (SABV) is a critical determinant of pharmacokinetics, pharmacodynamics, and toxicity in nonclinical studies. This review highlights how inappropriate neglect of sex differences compromises animal welfare, scientific reproducibility, and regulatory compliance.
Kenta Onuma, Masaki Watanabe, Nobuya Sasaki   +2 more
wiley   +1 more source

Fatty acid composition in the yolk and yolk sac, embryo development, IGF-I and VEGF-A gene expressions and hatching results in eggs obtained from local and commercial breeders. [PDF]

Trop Anim Health Prod
Rharbaoui H, Ünal N, Onbaşılar EE, Yakan A.   +3 more
europepmc   +1 more source

Research progress in animal models of dry eye disease: Types, mechanisms, and application prospects

Animal Models and Experimental Medicine, EarlyView.
Pivotal multifactorial animal models for translational dry eye disease research. Abstract Dry eye disease (DED) is a prevalent and complex multifactorial ocular surface disorder, leading to significant visual discomfort and diminished quality of life.
Jinshen Liu, Jiaqi Chen, Zhonghui Li, Jiamin Zhou, Hui Zhang, Yujia Yu, Feng Cheng, Jie Bao, Chunhan Feng, Xiangqu Yu, Zhao Xia, Rao Ding, Xiang Li   +12 more
wiley   +1 more source

Comparative Growth Performance and Intestinal Morphological Development Between Liangshan Yanying Chicken and Arbor Acres Chicken During the Brooding Stage. [PDF]

Animals (Basel)
Sun Z, Li T, Chen C, Wu C, Zhuo R, Wang D, Deng Q, Yang C, Wang J, Yang H, Huang Z.   +10 more
europepmc   +1 more source

Correlations Between Osteocyte Lacuno‐Canalicular Network and Material Characteristics in Healthy and Mechanically Stimulated Murine Tibiae

Advanced NanoBiomed Research, EarlyView.
This article reveals how calcium content, mineral nanostructure, and lacuno‐canalicular network (LCN) organization interact to shape bone heterogeneity in mouse tibiae. Advanced multimodal imaging uncovers that mechanical loading promotes mature mineral structures even in low‐calcium regions, highlighting LCN‐driven mineralization and offering new ...
Victoria Schemenz, Maximilian Rummler, Alexander van Tol, Isabela Vitienes, Tobias Thiele, Markus A. Hartmann, Manfred Burghammer, Peter Fratzl, Richard Weinkamer, Bettina M. Willie, Wolfgang Wagermaier   +10 more
wiley   +1 more source

Avian cecal microbiome response and resilience to Newcastle disease are dictated by breed background. [PDF]

Front Syst Biol
Ameer A, Saleem F, Keating C, Afzal F, Irshad H, Ahmed K, Sattar S, Ijaz UZ, Javed S.   +8 more
europepmc   +1 more source

Exergy and Economic Analysis of Hybrid Mechanical Vapor Compression and Membrane Distillation

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Hybridization of two or more desalination processes has been identified as an attractive option for improved energy efficiency and recovery rate. To appropriately assess the performance enhancement of hybrid desalination systems, an integrated approach for energy, exergy, economic, and environmental investigations should be adopted. This study
Emad Ali, Jamel Orfi
wiley   +1 more source

Genetic Structure and Selective Signature Analysis of Xinjiang Local Sheep Populations. [PDF]

Animals (Basel)
Luo C, Yasen M, Bai F, Hao G, Abulaizi A, Yu L, Ainivaner N, Ji X, Zhang Y, Yu J, Zhang Y.   +10 more
europepmc   +1 more source

Evaluating nitrogen uptake: Methods and applications for plant research

Applications in Plant Sciences, EarlyView.
Abstract Nitrogen is an essential nutrient for the growth and development of plants, aiding many physiological and biological functions. Due to the high demand for the nutrient, it is common for agricultural production systems to fertilize crop fields with large quantities of nitrogen.
Emilia Pierce, Amanda Rasmussen, Alexandra Huddell, Erin E. Sparks   +3 more
wiley   +1 more source

Whole-genome sequencing reveals genomic diversity and selection signatures for adaptation in South African Afrikaner and Bonsmara cattle. [PDF]

Front Genet
Alberts D, van Marle-Köster E, Joubert F, Berry DP.   +3 more
europepmc   +1 more source