Results 101 to 110 of about 4,856 (294)
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
The relative index for corner singularities
, 2006 We study pseudo-differential operators on a cylinder R x B where B has conical singularities. Configurations of that kind are the local model of corner singularities with cross section B.
Harutjunjan, Gohar +1 more
core +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
The K-theory of (compound) Du Val singularities [PDF]
, 2020 This thesis gives a complete description of the Grothendieck group and divisor class group for large families of two and three dimensional singularities. The main results presented throughout, and summarised in Theorem 8.1.1, give an explicit description
Steele, Kellan
core
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Holomorphic arcs on singularities
, 2015 The study of formal arcs was initiated by Nash in a 1967 preprint. Arc spaces of smooth varieties have a rather transparent structure but difficult problems arise for arcs passing through singularities.
Némethi, András +3 more
core +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Terminal singularities, Milnor numbers, and matter in F-theory [PDF]
, 2018 We initiate a systematic investigation of F-theory on elliptic fibrations with singularities which cannot be resolved without breaking the Calabi–Yau condition, corresponding to Q-factorial terminal singularities.
Arras, Philipp +5 more
core +1 more source
Generalized toric polygons, T-branes, and 5d SCFTs
SciPost Physics5d Superconformal Field Theories (SCFTs) are intrinsically strongly-coupled UV fixed points, whose realization hinges on string theoretic methods: they can be constructed by compactifying M-theory on local Calabi-Yau threefold singularities or ...
Antoine Bourget, Andrés Collinucci, Sakura Schäfer-Nameki
doaj +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source