Results 111 to 120 of about 9,654,838 (253)

Bulk-local-density-of-state correspondence in topological insulators. [PDF]

Nat Commun, 2023
Xie B, Huang R, Jia S, Lin Z, Hu J, Jiang Y, Ma S, Zhan P, Lu M, Wang Z, Chen Y, Zhang S.   +11 more
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Productivity and Local Workforce Composition [PDF]

This chapter examines the link between firm productivity and the population composition of the areas in which firms operate. We combine annual firm-level microdata on production, covering a large proportion of the New Zealand economy, with area-level ...
Richard Fabling, David C. Maré
core  

Nuclear Quantum Effects Made Accessible: Local Density Fitting in Multicomponent Methods. [PDF]

J Chem Theory Comput, 2023
Hasecke L, Mata RA.
europepmc   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Direct Measurement of the Local Density of Optical States in the Time Domain. [PDF]

ACS Photonics, 2023
Ter Huurne SET, Peeters DBL, Sánchez-Gil JA, Rivas JG.   +3 more
europepmc   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Population size or population density? An empirical examination of scale economies in South Australian local government, 2015/16

, 2018
Advocates of amalgamation typically claim that substantial scale economies flow from municipal mergers, which generate larger local government entities by population size.
Carolyn Tran, Kortt, Michael A, Kortt, Michael, Tran, Carolyn (R20673), Michael Kortt, Tran, Carolyn, Dollery, Brian, Brian Dollery   +7 more
core   +1 more source

Spatially local energy density of gravitational waves

Journal of High Energy Physics
We propose a new set of BMS charges at null infinity, characterized by a super-translation flux that contains only the ‘hard’ term. This is achieved with a specific corner improvement of the symplectic 2-form, and we spell the conditions under which it ...
Antoine Rignon-Bret, Simone Speziale
doaj   +1 more source