Results 161 to 170 of about 27,502,073 (401)
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
DE MINIMIS AID FOR LOCAL ECONOMY DEVELOPMENT [PDF]
Considering the current particular economic situation but also the community regulations developed by the EU Commission to diminish the crisis effects, we believe that local institutions should still take into consideration measures to encourage ...
MOGA ILIE, TILEAGÃ COSMIN
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Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Local Financial Development and the Aid-Growth Relationship [PDF]
With official development assistance (ODA) set to rise as countries strive to meet the Millennium Development Goals (MDGs), aid effectiveness remains an important area of development policy. An increasing number of studies support the notion that ODA can
Nkusu, Mwanza, Sayek, Selin
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ANALISIS PENGUKURAN KINERJA KEUANGAN PEMERINTAH DAERAH TAPAL KUDA DI JAWA TIMUR DITINJAU DARI SEGI EFISIENSI DAN EFEKTIFITAS [PDF]
, 2007 This research is a case study on horseshoe Local Government in East Java under the title "Analysis of Financial Performance Measurement In Local Government horseshoe East Java Based View of Efficiency and Effectiveness" Peneliltian aim is to describe and
Liliyana, Liliyana
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Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Impact of Shopping Tourism for the Retail Trade as a Strategy for the Local Development of Cities. [PDF]
Front Psychol, 2020 Muro-Rodríguez AI +2 more
europepmc +1 more source