Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
The development and year one implementation of the Local Justice Reinvestment Pilot [PDF]
, 2013 This report focuses on the initial findings from a process evaluation of the Local Justice Reinvestment pilot (commissioned by the Ministry of Justice), which examines the early development and implementation of the pilot in the first test year.
Barraclough, Nicola +5 more
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Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Economies of Scale and Efficiency in the Wastewater Treatment Sector: A Decision Tree Approach
Applied SciencesIn this study, we use the efficiency analysis trees (EAT) model to evaluate the efficiency of wastewater treatment plants (WWTPs), focusing on identifying the key variables that enhance their performance.
Vicent Hernández-Chover +3 more
doaj +1 more source
An Introduction to Food Cooperatives in the Bekaa Valley, Lebanon: Territorial Actors and Potential Levers to Local Development Through Culinary Heritage. [PDF]
Food Ethics, 2020 Jalkh R +2 more
europepmc +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Towards a Sustainable Local Development of Instructional Material: An Impact Assessment of Locally Produced Videos on EFL Learners' Skills and Individual Difference Factors. [PDF]
Front Psychol, 2020 Lasekan O, Godoy M.
europepmc +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Social Responsibility as a Driver for Local Sustainable Development [PDF]
The increased interconnection among local and global players induced by globalization, as well as the need for a complete application of the “subsidiarity principle”, calls for a re-thinking of the “corporate social responsibility” concept.
Cecilia Mezzano +2 more
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The development of local solar irradiance for outdoor computer graphics rendering [PDF]
, 2005 Atmospheric effects are approximated by solving the light transfer equation, LTE, of a given viewing path. The resulting accumulated spectral energy (its visible band) arriving at the observer’s eyes, defines the colour of the object currently on the ...
Busu, Ibrahim +6 more
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