Results 141 to 150 of about 1,563,028 (315)

The role of local communities in sustaining education in Burma’s conflict zones

Revue Internationale d’Éducation de Sèvres
The development and sustainable learning opportunities in Myanmar’s public schools and alternative education services have greatly benefited from local communities’ support.
Peter Kamtungtuang Suante
doaj   +1 more source

HIV-1-Host Interaction in Gut-Associated Lymphoid Tissue (GALT): Effects on Local Environment and Comorbidities. [PDF]

Int J Mol Sci, 2023
Moretti S, Schietroma I, Sberna G, Maggiorella MT, Sernicola L, Farcomeni S, Giovanetti M, Ciccozzi M, Borsetti A.   +8 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Local environment drives rapid shifts in composition and phylogenetic clustering of seagrass microbiomes. [PDF]

Sci Rep, 2023
Kardish MR, Stachowicz JJ.
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Model’s parameter sensitivity assessment and their impact on Urban Densification using regression analysis

Geography and Sustainability
The impact of different global and local variables in urban development processes requires a systematic study to fully comprehend the underlying complexities in them.
Anasua Chakraborty, Mitali Yeshwant Joshi, Ahmed Mustafa, Mario Cools, Jacques Teller   +4 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Accurate and efficient protein sequence design through learning concise local environment of residues. [PDF]

Bioinformatics, 2023
Huang B, Fan T, Wang K, Zhang H, Yu C, Nie S, Qi Y, Zheng WM, Han J, Fan Z, Sun S, Ye S, Yang H, Bu D.   +13 more
europepmc   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

‘Local Food’ Systems in County Durham: The capacities of community initiatives and local food businesses to build a more resilient local food system [PDF]

, 2011
This thesis provides a critical assessment of the capacities of ‘local food’ businesses and community-led local food initiatives - in County Durham, North East England - to build resilience into our food systems.
MYCOCK, AMY,ELIZABETH
core