Results 121 to 130 of about 1,563,028 (315)

Challenges in Creating a Disaster Resilient Built Environment [PDF]

, 2014
With the increase in occurrences of high impact disasters, the concept of risk reduction and resilience is widely recognised. Recent disasters have highlighted the exposure of urban cities to natural disasters and emphasised the need of making cities ...
Chamindi Malalgoda, Amaratunga, Dilanthi, Richard Haigh, Haigh, Richard, Malalgoda, Chamindi, Dilanthi Amaratunga   +5 more
core   +1 more source

Working with Cultural Heritage from the Local Environment: Analysis of Perceptions of Future Teachers

Social Sciences
Cultural heritage refers to the set of tangible and intangible assets that a society inherits from its ancestors and transmits to future generations.
Patricia Suárez-Álvarez, Alejandro Otero-Varela   +1 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Local governance and climate change : reflections on the Swedish experience [PDF]

, 2007
The focus of this article is the Swedish experience of local governance and climate change, including mitigation and adaptation. The municipal response to these two challenges is set within a broader policy context that acknowledges Sweden as a pioneer ...
Granberg, Mikael,, Elander, Ingemar,
core   +1 more source

Localization in multipath environments [PDF]

, 2019
This thesis focuses on the design of localization schemes and algorithms which work in multipath environments. Traditionally, conventional localization schemes work based on the assumption that the reference devices (RDs) are always in Line-of-Sight (LOS) with the mobile device (MD) to locate the MD.
openaire   +2 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Schools and their local communities: between competition, cooperation and mobilisation for learning

Revue Internationale d’Éducation de Sèvres
In many countries, the relationship between schools and local communities is evolving in step with territorial changes (urbanisation and metropolisation, widening social and geographical inequalities, migration, geopolitical conflicts), as well as new ...
David Giband, Laurent Rieutort
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Programs and services [1989 - Kansas Department of Health and Environment] [PDF]

, 1989
"July, 1989.""This booklet briefly describes the programs and services provided by the Kansas Department of Health and Environment (KDHE). Legislative authority for Department activities appears in sections of various Kansas statutes.
Kansas. Department of Health and Environment. Office of Public Information.
core  

Universités privées à Dakar : des pôles éducatifs arrimés aux ressources de la ville-centre

Revue Internationale d’Éducation de Sèvres
In Dakar, private universities are developing by drawing on the resources of the city centre, particularly around Cheikh Anta Diop University. They are largely dependent on public sector teaching staff and benefit from the city’s infrastructure.
Kevin Mary, Jean Alain Goudiaby
doaj   +1 more source