Results 101 to 110 of about 6,425,933 (304)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Impact of the unplanned excision on the oncological outcomes of patients with soft tissue sarcomas: a single-center retrospective review of 490 patients [PDF]
, 1994 OBJECTIVE: This study aimed to (1) compare the oncological results of patients who underwent re-excision after unplanned excision with those who underwent planned excision and (2) analyze the impact of local recurrences on oncological outcomes.
Sabah, Dündar +13 more
core +1 more source
Dermatofibrosarcoma Protuberans Presenting as a Long-standing Infraclavicular Mass in a 79-year-old Male: A Case Report [PDF]
Journal of Clinical and Diagnostic ResearchDermatofibrosarcoma Protuberans (DFSP) is a rare, low to intermediate-grade cutaneous soft-tissue sarcoma that is characterised by slow growth, local aggressiveness, and a high recurrence rate if inadequately excised.
Subhangi Parmar +4 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Journal of Bone Oncology, 2018 Current reports on prognostic factors for chondrosarcoma mainly involve patients in treatment centers. Few are based on multicenter or multi-eras.
Zhigang Nie, Qiang Lu, Hao Peng
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Short-term outcomes after primary total mesorectal excision (TME) versus local excision followed by completion TME for early rectal cancer:population-based propensity-matched study [PDF]
Background: Colorectal cancer screening programmes have led to a shift towards early-stage colorectal cancer, which, in selected cases, can be treated using local excision.
van Dieren, Susan +6 more
core +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Supplemental material: Comparative Outcomes of Deroofing and Wide Local Excision for Advanced Hidradenitis ...
Mehta, Shanti
core +1 more source
Local Excision of Rectal Cancer.
Nippon Daicho Komonbyo Gakkai Zasshi, 1992 東大第1外科において13例のm癌,18例のsm癌,4例のpm癌,1例のa1癌(合計36例)に対して局所切除術が施行された('67-'91).局所切除術のほとんどがRb癌に対して施行され(83.3%),より肛門管に近いものに経仙骨的切除や経肛門的切除が選択されていた.有茎性の病変は4例と少なく,無茎(Is),平坦陥凹型(IIa+IIc)病変がそれぞれ9例と多くかった(50%).絨毛腫瘍や結節集簇様病変には経仙骨的切除術が行われていた(6例中4例).経肛門的切除は2cm以下に,経仙骨的・括約筋的切除は4cm以上の病変に行われていた.その結果,縫合不全は2例であり(5.6%),sm癌の癌遺残または局所再発例は2例(11.1%)であった.再発例は経肛門的切除でリンパ管侵襲陽性であり ...
Sawada, T., Muto, T.
openaire +2 more sources