The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Mathematical Models Arising in the Fractal Forest Gap via Local Fractional Calculus
Abstract and Applied Analysis, 2014 The forest new gap models via local fractional calculus are investigated. The JABOWA and FORSKA models are extended to deal with the growth of individual trees defined on Cantor sets. The local fractional growth equations with local fractional derivative
Chun-Ying Long +2 more
doaj +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
A sufficient condition for local controllability of a Caputo type fractional differential inclusion
Annals of the West University of Timisoara: Mathematics and Computer Science, 2022 We consider a Cauchy problem for a fractional differential inclusion defined by a Caputo type fractional derivative and we obtain a sufficient condition for local controllability along a reference trajectory in terms of a certain fractional variational ...
Cernea Aurelian
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
A Simple Reliable Hybrid Method Based on Taylor Series for Generalized Local Fractional Nonlinear Singular Differential Equations [PDF]
Journal of Applied and Computational MechanicsThis paper proposes a local fractional derivative of order α when α > 1 ([1]). We also propose a simple method and refer to it as the hybrid Taylor series method, which solves a class of generalized local fractional systems of singular differential ...
Amit Verma +4 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Diffusion Equation Including Local Fractional Derivative and Dirichlet Boundary Conditions
, 2023 In this research, we discuss the construction of analytic solution of homogenous initial boundary value problem including PDEs of fractional order.
ÇETİNKAYA, SÜLEYMAN, DEMİR, ALİ
core
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
A design methodology to enable sampling PLLs to synthesise fractional-N frequencies [PDF]
, 2011 A novel design methodology is proposed to enable sampling phase-locked loops (SPLL) to synthesise fractional-N frequencies. To date, SPLL can only generate integer-N frequencies.
Xu, Tao +2 more
core +1 more source