Results 71 to 80 of about 6,401,396 (254)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
A remark on local fractional calculus and ordinary derivatives
Open Mathematics, 2016 In this short note we present a new general definition of local fractional derivative, that depends on an unknown kernel. For some appropriate choices of the kernel we obtain some known cases. We establish a relation between this new concept and ordinary
Almeida Ricardo +2 more
doaj +1 more source
A new class of travelling wave solutions for local fractional diffusion differential equations
Advances in Difference Equations, 2020 In this paper, we investigate a 3-D diffusion equation within the scope of the local fractional derivative. For this model, we establish local fractional vector operators and a local fractional Laplace operator defined on Cantor-type cylindrical ...
Ziyue Shi, Wei Qi, Jing Fan
doaj +1 more source
Pricing European and Barrier Options in the Fractional Black-Scholes Market [PDF]
The aim of this paper is to obtain the valuation formulas for European and barrier options if the underlying of the option contract is supposed to be driven by a fractional Brownian motion with Hurst parameter greater than 0.5.
Ciprian Necula
core
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Abstract and Applied Analysis, 2013 The one-dimensional heat equations with the heat generation arising in fractal transient conduction associated with local fractional derivative operators are investigated.
Ai-Ming Yang +3 more
doaj +1 more source
Fractional Calculus Operators and the Mittag-Leffler Function
, 2022 This book focuses on applications of the theory of fractional calculus in numerical analysis and various fields of physics and engineering. Inequalities involving fractional calculus operators containing the Mittag–Leffler function in their kernels are ...
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Local fractional Newton’s inequalities involving generalized harmonic convex functions
Advances in Difference Equations, 2020 A new auxiliary result based on a three step quadratic kernel utilizing the concepts of local fractional calculus is obtained. Using this new auxiliary result we have several new Newton type inequalities whose power q of local fractional derivative in ...
Sabah Iftikhar +3 more
doaj +1 more source
A Framework for Derivative Pricing in the Fractional Black-Scholes Market [PDF]
The aim of this paper is to develop a framework for evaluating derivatives if the underlying of the derivative contract is supposed to be driven by a fractional Brownian motion with Hurst parameter greater than 0.5.
Ciprian Necula
core