Results 81 to 90 of about 145,243 (265)
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Triangular bases of integral closures
, 2014 In this work, we consider the problem of computing triangular bases of integral closures of one-dimensional local rings. Let $(K, v)$ be a discrete valued field with valuation ring $\mathcal{O}$ and let $\mathfrak{m}$ be the maximal ideal.
Stainsby, Hayden D.
core +1 more source
Local integration by parts and Pohozaev identities for higher order fractional Laplacians
Discrete and Continuous Dynamical Systems, 2015 The sign of the boundary term in Theorem 1.5 has been ...
Ros Oton, Xavier +1 more
openaire +4 more sources
FEBS Open Bio, EarlyView.Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
ON A PROBLEM FOR THE LOADED MIXED TYPE EQUATION WITH FRACTIONAL DERIVATIVE
Vestnik KRAUNC: Fiziko-Matematičeskie Nauki, 2016 An existence and an uniqueness of solution of local boundary value problem with discontinuous matching condition for the loaded parabolic-hyperbolic equation involving the Caputo fractional derivative and Riemann-Liouville integrals have been ...
Abdullaev, O.K.
doaj +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Aging and Cancer, EarlyView.This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Generalizations of Hölder’s and Some Related Integral Inequalities on Fractal Space
Journal of Function Spaces and Applications, 2013 Based on the local fractional calculus, we establish some new generalizations of Hölder’s inequality. By using it, some related results on the generalized integral inequality in fractal space are investigated in detail.
Guang-Sheng Chen
doaj +1 more source