Results 71 to 80 of about 10,422 (254)

Generalized Pompeiu type inequalities for local fractional integrals and its applications

open access: yesApplied Mathematics and Computation, 2016
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Erden, Samet   +2 more
openaire   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

The Existence of Positive Solutions for a p-Laplacian Tempered Fractional Diffusion Equation Using the Riemann–Stieltjes Integral Boundary Condition

open access: yesMathematics
In this paper, we focus on the existence of positive solutions for a class of p-Laplacian tempered fractional diffusion equations involving a lower tempered integral operator and a Riemann–Stieltjes integral boundary condition. By introducing certain new
Lishuang Li   +3 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Generalized fractional integrals in the vanishing generalized weighted local and global Morrey spaces

open access: yesFilomat, 2023
In this paper, we prove the boundedness of generalized fractional integral operators I? in the vanishing generalized weighted Morrey-type spaces, such as vanishing generalized weighted local Morrey spaces and vanishing generalized weighted global Morrey spaces by using weighted Lp estimates over balls.
openaire   +3 more sources

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

Local integration by parts and Pohozaev identities for higher order fractional Laplacians

open access: yesDiscrete and Continuous Dynamical Systems, 2015
The sign of the boundary term in Theorem 1.5 has been ...
Ros Oton, Xavier   +1 more
openaire   +4 more sources

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