Results 51 to 60 of about 145,243 (265)

Variational Iteration Transform Method for Fractional Differential Equations with Local Fractional Derivative

open access: yesAbstract and Applied Analysis, 2014
We propose the variational iteration transform method in the sense of local fractional derivative, which is derived from the coupling method of local fractional variational iteration method and differential transform method.
Yong-Ju Yang, Liu-Qing Hua
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Certain Hadamard Proportional Fractional Integral Inequalities

open access: yesMathematics, 2020
In this present paper we study the non-local Hadmard proportional integrals recently proposed by Rahman et al. (Advances in Difference Equations, (2019) 2019:454) which containing exponential functions in their kernels.
Gauhar Rahman   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Inhomogeneous Fractional Diffusion Equations [PDF]

open access: yes, 2005
2000 Mathematics Subject Classification: Primary 26A33; Secondary 35S10, 86A05Fractional diffusion equations are abstract partial differential equations that involve fractional derivatives in space and time.
Baeumer, Boris   +2 more
core   +1 more source

Some Generalized Inequalities Involving Local Fractional Integrals and their Applications for Random Variables and Numerical Integration [PDF]

open access: yesJournal of Applied Mathematics, Statistics and Informatics, 2016
AbstractWe establish generalized pre-Grüss inequality for local fractional integrals. Then, we obtain some inequalities involving generalized expectation,p−moment, variance and cumulative distribution function of random variable whose probability density function is bounded.
Erden, Samet   +3 more
openaire   +3 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

LDG schemes with second order implicit time discretization for a fractional sub-diffusion equation

open access: yesResults in Applied Mathematics, 2019
In this paper, we propose new local discontinuous Galerkin (LDG) schemes for solving a time fractional sub-diffusion equation. The new LDG schemes is constructed rely on the splitting of time fractional derivative and space derivative.
Can Li, Xiaorui Sun, Fengqun Zhao
doaj   +1 more source

On a Fractional Operator Combining Proportional and Classical Differintegrals

open access: yesMathematics, 2020
The Caputo fractional derivative has been one of the most useful operators for modelling non-local behaviours by fractional differential equations. It is defined, for a differentiable function f ( t ) , by a fractional integral operator applied to
Dumitru Baleanu   +2 more
doaj   +1 more source

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