Results 101 to 110 of about 193,471 (315)
Security Governance, Policing, and Local Capacity
, 2012 The security governance of South Africa has faced immense challenges amid post-apartheid constitutional and political transformations. In many cases, policing and governmental organizations have failed to provide security and other services to the ...
Shearing, Clifford, Froestad, Jan
core
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
The hollowing-out of local democracy and the 'fatal conceit' of governing without government [PDF]
, 2000 On 4th May 2000, Ken Livingstone was elected Mayor of London on a turn-out of only 33.6%, a day when around 30% of voters turned out in local council elections.
Davies, Jonathan S. +2 more
core +1 more source
HeliyonThis paper responds to the limited literature on perceptions of fire disaster risks associated with the siting of fuel stations in dense residential areas in African cities.
Ibrahim Abu Abdulai +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
The Foundations of Multi-channel Neighborhood Governance [PDF]
The book presents various aspects of the current urban development in the context of the recent rapid growth of the ICT sector. It focuses on the local scale, in line with the notion that the neighborhood is the fundamental component of any urban area ...
Damurski, Łukasz
core +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
A call to strengthen local governance for preventing and mitigating global crises. [PDF]
One Health, 2023 Frias L, Guerrero-Sanchez S.
europepmc +1 more source
Juridical Journal of Samara University, 2018 The study of problematic issues of development of existing legal forms of selforganization of municipalities as self-governing bodies, and their interaction with public authorities in the form of governing bodies, including those operating at the grassroots level, is a long-standing object of scientific research of scientists. The article considers the
openaire +2 more sources
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source