Results 31 to 40 of about 78,404 (295)

THE DEVELOPMENT OF CULTURAL SECTOR IN THE RURAL TERRITORIES OF THE REPUBLIC OF CRIMEA: DEVELOPMENT PRIORITIES CHOICE [PDF]

open access: yesKrymskij Naučnyj Vestnik, 2016
The optimization of demand pattern in cultural sector is one of the most important government’s tasks. Federal authorities, society, local authorities, several individual, enterprises, social organizations and mass media have an opportunity to influence ...
Olga Pernatskaia
doaj  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Groping for Autonomy: The Federal Government and American Hospitals [PDF]

open access: yes, 1999
This article chronicles the slow but steady emergence of countervailing power in the hospital industry since mid-century. The transformation of American health care policymaking reflects the federal government\u27s growing fiscal obligations as the ...
Hackey, Robert B.
core   +1 more source

Parliamentary committees in Zambia's Third Republic: partial reforms; unfinished agenda [PDF]

open access: yes, 2002
This article critically examines the contribution of parliamentary committees in Zambia to democratic government. Several committees are of long-standing, including the Committee on Government Assurances and Committee on Delegated Legislation; others ...
Burnell, Peter J.
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Ethical Concerns of School Closures for Low-Income School Aged Children

open access: yesVoices in Bioethics, 2020
Photo by Jeremy Alford on Unsplash INTRODUCTION  COVID-19 is the latest threat to educational equity.1 The use of technology for work, school, and social interaction has increased for many Americans yet not all have access to technology necessary to ...
Shami-Iyabo Mitchell
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Rail Privatisation: The Practice – An Analysis of Seven Case Studies [PDF]

open access: yes, 1994
After a brief description of the proposals for rail privatisation in Great Britain, this paper contrasts these with the proposals and experience in other countries around the world.
Nash, C.A.   +3 more
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

A new technology-driven concept of care. Insights from a Norwegian case-study

open access: yesInternational Journal of Integrated Care, 2019
“Think big – Start small – Scale fast” declares the Norwegian Government in launching the first National Program for developing and implementing welfare technology in local care services.
Ziglioli Gloria
doaj   +1 more source

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