Results 51 to 60 of about 78,725 (297)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Parliamentary committees in Zambia's Third Republic: partial reforms; unfinished agenda [PDF]
, 2002 This article critically examines the contribution of parliamentary committees in Zambia to democratic government. Several committees are of long-standing, including the Committee on Government Assurances and Committee on Delegated Legislation; others ...
Burnell, Peter J.
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Trials, 2017 Background Female sterilization by tubal ligation is a safe, extremely effective, and permanent way to limit childbearing. It is the most popular modern contraceptive method worldwide.
Mark A. Barone +8 more
doaj +1 more source
Performance of public tasks by companies of local government units
Central European Review of Economics & Finance, 2017 The present article focuses on the issue of the provision of services of general economic interest by companies of local government units. Various parts discuss the basic requirements for entrusting the provision of this type of services to commercial companies, with particular reference to phenomena observed on a practical basis. It also addresses the
openaire +2 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Rail Privatisation: The Practice – An Analysis of Seven Case Studies [PDF]
, 1994 After a brief description of the proposals for rail privatisation in Great Britain, this paper contrasts these with the proposals and experience in other countries around the world.
Nash, C.A. +3 more
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The Access to the ICT Network as a Public Task of Local Government
Lex localis - Journal of Local Self-Government, 2021 The purpose of this paper is to describe the duties of local government units under the legal conditions related to access to the ICT network in Poland. Establishing public-private partnerships in the telecommunications sector, which is a field closely tied with cybersecurity, seems inevitable and necessary.
openaire +2 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Proposal for preparing the Lao legal framework Plan 2000 [PDF]
, 1997 This is a proposal for Lao PDR's Plan 2000 submitted by professors Ann and Bob Seidman, which was aimed at helping Lao PDR to strengthen its legal framework and legislative ...
Seidman, Ann, Seidman, Robert B.
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