Results 41 to 50 of about 78,725 (297)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Dyslexia in the Workplace: A Guide for Unions [PDF]
, 2004 [Excerpt]We have written this guide principally for trade union members and their representatives. In it we aim to help foster a fuller understanding of dyslexia and its effects on employees[.
Brian Hagan
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Ethical Concerns of School Closures for Low-Income School Aged Children
Voices in Bioethics, 2020 Photo by Jeremy Alford on Unsplash INTRODUCTION COVID-19 is the latest threat to educational equity.1 The use of technology for work, school, and social interaction has increased for many Americans yet not all have access to technology necessary to ...
Shami-Iyabo Mitchell
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Support and intervention arrangements [PDF]
, 2013 Nottingham Trent University's Emergency Services Research Unit have been carrying out research into the new National Framework for Fire and Rescue Services since the former Fire Minister Bob Neill announced a strategic review of the framework shortly ...
Greenhalgh, K, Murphy, P
core
A new technology-driven concept of care. Insights from a Norwegian case-study
International Journal of Integrated Care, 2019 “Think big – Start small – Scale fast” declares the Norwegian Government in launching the first National Program for developing and implementing welfare technology in local care services.
Ziglioli Gloria
doaj +1 more source
Municipal waste management as a local government task – legal and organizational challenges
Annals of Marketing Management & Economics, 2015 The article presents the organisational and legal conditions behind a municipal waste management system. The authors reviewed the subject literature on the functioning of local government and public services theory, focusing on municipal waste management. The paper also contains acts governing international and national law.
Anna Milewska, Karolina Bogucka
openaire +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source