Results 21 to 30 of about 597,706 (313)
SAGE OpenThe rapid integration of artificial intelligence (AI) into organizational processes presents both opportunities and challenges for human resource management (HRM), yet a systematic understanding of its scholarly development remains limited.
John William Kasubi +2 more
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Assessing the Energy Crisis in South Africa: The Socio-Economic Implication and Challenges Ahead [PDF]
E-Journal of Humanities, Arts and Social SciencesThis paper examined the socio-economic implications caused by the current energy crisis South Africa is facing. Although the crisis is not at its worst stage when compared to other countries in Africa, there are still challenges ahead if the crisis at ...
Kazeem Oyedele Lamidi +1 more
doaj +1 more source
Local self-government or local co-governance?
Lex localis - Journal of Local Self-Government, 2010 The article discusses “local self-government”, a core concept in a charter of the Council of Europe, and departs from a debate in the Norwegian Parliament about constitutional protection of local self-government. Newly, such a change was voted down, and this serves as an opportunity to question the idea about local self-government in a time when there ...
openaire +3 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Success, challenges and prospects of decentralization in Africa: a systematic review
Cogent Social SciencesDecentralization remains a global development approach. African countries have been using decentralization by devolution to realize their development vision. This study assesses the success, challenges, and prospects of decentralization in Africa.
Rogers Rugeiyamu, Adam Msendo
doaj +1 more source
The Municipalities and INSPIRE – Any Connection?
Geoforum Perspektiv, 2014 On the surface, the municipalities are neither data owners nor data systems managers in connection with Denmark's reporting of data to INSPIRE. However, if you dig a little deeper in the actual data reports, you will see that the municipalities are ...
Inge Flensted
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Engaging the local government in research & extension: The ACIAR-ICM-landcare experience
Annals of Tropical Research, 2017 Agricultural research and extension are important elements for improving agricultural production and food systems. It is said that the enhancement of traditional farming into science-based agriculture requires expeditious transfer of research results ...
Evy Elago-Carusos +2 more
doaj +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source