Results 61 to 70 of about 1,408,242 (313)

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Governance in urban development crisis situations

open access: yesAnali Hrvatskog Politološkog Društva, 2008
Urban shrinking processes are increasingly recognized as a phenomenon for research in urban politics, encompassing entire cities or parts of it as well as metropolitan areas that are experiencing a fundamental decline in both their economic and social ...
Jörg Rober
doaj  

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

FISCAL POLICY DISCLOSURE IN INDONESIAN LOCAL GOVERNMENTS

open access: yesJurnal Akuntansi dan Auditing Indonesia, 2016
Studi ini meneliti tingkat pengungkapan informasi kebijakan fiskal dalam laporan keuangan pemerintah daerah Indonesia. Indonesia adalah sebuah negara berkembang yang baru saja melalukan reformasi keuangan negara secara komprehensif.
Johan Arifin, Greg Tower, Stacey Porter
doaj   +1 more source

Local Governments Debt

open access: yes, 2016
[Excerpt] In the public sector, debt results when public organizations borrow money from an individual or another organization with the promise of repayment at a later date (Mikesell 2013).
openaire   +2 more sources

Mainstreaming Disaster Risk Management in Local Governments [PDF]

open access: yes
The Philippines` geographical location makes it a disaster-prone country. In the Southeast Asian region, it ranks the highest in terms of the multiple climate hazard index measure.
Llanto, Gilberto M.
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

COMPETENCE OF LOCAL SELF-GOVERNMENTS: DEBATABLE ISSUES

open access: yesПравоприменение, 2018
Subject. The article is devoted to the discussion issues of competence of local self-government.The purpose of this paper is to show that the federal government passes such laws in order to build a single “power vertical” from a rural settlement to a ...
Y. Blagov
doaj   +1 more source

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