Results 171 to 180 of about 24,015,970 (365)

Accounting for minimum data required to train a machine learning model to accurately monitor Australian dairy pastures using remote sensing

open access: yesScientific Reports
Precision in grazing management is highly dependent on accurate pasture monitoring. Typically, this is often overlooked because existing approaches are labour-intensive, need calibration, and are commonly perceived as inaccurate.
Martin Correa-Luna   +8 more
doaj   +1 more source

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

open access: yesMolecular Oncology, EarlyView.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric   +11 more
wiley   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

A note on the localization of $J$-groups [PDF]

open access: yesHiroshima Mathematical Journal, 1999
Let $\widetilde{JO}(X)=\widetilde{KO}(X)/TO(X)$ be the J-group of a connected finite CW complex X. We Obtain two computable formulas of $TO(X)_{(p)}$, the localization of $TO(X)$ at a prime p. Then we show how to use these two formulas of $TO(X)_{(p)}$ to find the J-orders of elements of $\widetilde{KO}(CP^m)$, at least the 2 and 3 primary factors of ...
openaire   +3 more sources

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas   +15 more
wiley   +1 more source

Personality and Politics: Values, Traits, and Political Choice [PDF]

open access: yes, 2006
Claudio Barbaranelli   +4 more
core   +2 more sources

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

The Milky Way and the Local Group

open access: yes, 2016
The beauty and the charm of the Milky May (MW) have been celebrated by countless poets and writers of many Countries along the centuries (see e.g. the beautiful anthology of Piero Boitani 2012 ). The stellar nature of the MW was firstly observed by Galileo.
RAMPAZZO, ROBERTO   +13 more
openaire   +7 more sources

DYNAMICAL FRICTION IN THE LOCAL GROUP

open access: yesOdessa Astronomical Publications, 2013
In this paper we consider dynamical behavior of the astrophysical objects in the Local Group. The motion of Andromed and The Milky Way is studied. We distinguish two different models: for the first one we do not take into account the influence of the ...
A. V. Kudinova
doaj   +1 more source

Germline variants in CDKN2A wild‐type melanoma prone families

open access: yesMolecular Oncology, EarlyView.
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen   +5 more
wiley   +1 more source

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