Results 1 to 10 of about 10,144,297 (167)

A cortical shape-adaptive approach to local gyrification index. [PDF]

Med Image Anal, 2018
The amount of cortical folding, or gyrification, is typically measured within local cortical regions covered by an equidistant geodesic or nearest neighborhood-ring kernel. However, without careful design, such a kernel can easily cover multiple sulcal and gyral regions that may not be functionally related. Furthermore, this can result in smoothing out
Lyu I, Kim SH, Girault JB, Gilmore JH, Styner MA.   +4 more
europepmc   +9 more sources

Local gyrification index in probands with psychotic disorders and their first-degree relatives. [PDF]

Biol Psychiatry, 2014
Psychotic disorders are characterized by aberrant neural connectivity. Alterations in gyrification, the pattern and degree of cortical folding, may be related to the early development of connectivity. Past gyrification studies have relatively small sample sizes, yield mixed results for schizophrenia, and are scant for psychotic bipolar and ...
Nanda P, Tandon N, Mathew IT, Giakoumatos CI, Abhishekh HA, Clementz BA, Pearlson GD, Sweeney J, Tamminga CA, Keshavan MS.   +9 more
europepmc   +9 more sources

Altered Local Gyrification Index and Corresponding Functional Connectivity in Medication Free Major Depressive Disorder [PDF]

Frontiers in Psychiatry, 2020
A lot of previous studies have documented that major depressive disorder (MDD) is a developmental disorder. The cortical surface measure, local gyrification index (LGI), can well reflect the fetal and early postnatal neurodevelopmental processes.
Jiang Long, Jinping Xu, Xue Wang, Jin Li, Shan Rao, Huawang Wu, Weihong Kuang   +6 more
doaj   +7 more sources

Analysis of local gyrification index using a novel shape-adaptive kernel and the standard FreeSurfer spherical kernel – evidence from chronic schizophrenia outpatients [PDF]

Heliyon, 2020
Schizophrenia can be considered a brain disconnectivity condition related to aberrant neurodevelopment that causes alterations in the brain structure, including gyrification of the cortex.
Olga Płonka, Alicja Krześniak, Przemysław Adamczyk   +2 more
doaj   +8 more sources

A Longitudinal Study of Local Gyrification Index in Young Boys With Autism Spectrum Disorder. [PDF]

Cereb Cortex, 2019
Local gyrification index (LGI), a metric quantifying cortical folding, was evaluated in 105 boys with autism spectrum disorder (ASD) and 49 typically developing (TD) boys at 3 and 5 years-of-age. At 3 years-of-age, boys with ASD had reduced gyrification in the fusiform gyrus compared with TD boys.
Libero LE, Schaer M, Li DD, Amaral DG, Nordahl CW.   +4 more
europepmc   +10 more sources

Local gyrification index and sulcal depth as imaging markers of cognitive decline in Alzheimer’s disease [PDF]

Frontiers in Aging Neuroscience
PurposeTo investigate the correlation between cortical thickness (CT), sulcal depth (SD), local gyrification index (LGI), and cognitive scores in patients with Alzheimer’s disease (AD).MethodsA total of 200 patients with AD from 2014 to 2021 were ...
Yongsik Sim, Changmin Seo, Young-gun Lee, Byoung Seok Ye, Ilwoo Lyu, Ilwoo Lyu, Beomseok Sohn   +6 more
doaj   +7 more sources

Altered local gyrification index and corresponding functional connectivity in female depressed adolescents with suicide attempts and non-suicidal self-injury. [PDF]

Psychoradiology
Abstract Background Suicide attempts (SA) and non-suicidal self-injury (NSSI) are serious public health problems that frequently co-occur in adolescents females with major depressive disorder (MDD), yet their neurobiological distinctions remain unclear.
Yang L, Wang S, Ji Y, Gao X, Guo Z, Zhou Z, Yang Y, Xia Y, Huang H, Li J, Tian L.   +10 more
europepmc   +4 more sources

Local gyrification index in patients with major depressive disorder and its association with tryptophan hydroxylase-2 (TPH2) polymorphism. [PDF]

Hum Brain Mapp, 2017
AbstractThe tryptophan hydroxylase‐2 (TPH2) gene is considered a promising genetic candidate regarding its association with a predisposition to major depressive disorder (MDD). Local gyrification reflects the early neural development of cortical connectivity, and is regarded as a potential neural endophenotype in psychiatric disorders.
Han KM, Won E, Kang J, Kim A, Yoon HK, Chang HS, Son KR, Lee MS, Tae WS, Ham BJ.   +9 more
europepmc   +4 more sources

A gyrification analysis approach based on Laplace Beltrami eigenfunction level sets

NeuroImage, 2021
An accurate measure of the complexity of patterns of cortical folding or gyrification is necessary for understanding normal brain development and neurodevelopmental disorders.
Rosita Shishegar, Fabrizio Pizzagalli, Nellie Georgiou-Karistianis, Gary F. Egan, Neda Jahanshad, Leigh A. Johnston   +5 more
doaj   +3 more sources

Prefrontal-centered cortical alterations and network dysconnectivity in cocaine use disorder [PDF]

Frontiers in Psychiatry
BackgroundCocaine use disorder (CUD) is a chronic, relapsing condition with substantial clinical burden, yet its neurobiological basis remains incompletely understood, particularly in the socially vulnerable populations most affected in real-world ...
Leonardo Melo Rothmann, Eduardo Tavares Portolan, Nathalia Bianchini Esper, Breno Sanvicente-Vieira, Augusto Martins Lucas Bittencourt, Thiago Wendt Viola, Pedro Eugênio Ferreira, Simon Fristed Eskildsen, Alexandre Rosa Franco, Alexandre Rosa Franco, Alexandre Rosa Franco, Rodrigo Grassi-Oliveira, Rodrigo Grassi-Oliveira   +12 more
doaj   +2 more sources