Results 41 to 50 of about 10,144,297 (167)

Gyrification brain abnormalities as predictors of outcome in anorexia nervosa. [PDF]

, 2015
Gyrification brain abnormalities are considered a marker of early deviations from normal developmental trajectories and a putative predictor of poor outcome in psychiatric disorders.
TENCONI, ELENA, SANTONASTASO, PAOLO, Renzo, Manara, FAVARO, ANGELA, Daniela, Degortes, Renzo Manara, Angela Favaro, Elena Tenconi, Paolo Santonastaso, Daniela Degortes   +9 more
core   +1 more source

Altered cortical and subcortical morphometric features and asymmetries in the subjective cognitive decline and mild cognitive impairment

Frontiers in Neurology, 2023
IntroductionThis study aimed to evaluate morphological changes in cortical and subcortical regions and their asymmetrical differences in individuals with subjective cognitive decline (SCD) and mild cognitive impairment (MCI).
Jin Yang, Lingyan Liang, Yichen Wei, Ying Liu, Xiaocheng Li, Jiazhu Huang, Zhiguo Zhang, Zhiguo Zhang, Zhiguo Zhang, Linling Li, Linling Li, Demao Deng, Demao Deng   +12 more
doaj   +1 more source

Regionally decreased cortical gyrification in patients with major depressive disorder

European Psychiatry, 2023
Introduction Early neurodevelopmental deviations, such as abnormal cortical folding patterns, are a candidate biomarker for major depressive disorder (MDD).
K.-M. Han, Y. Kang, B.-J. Ham
doaj   +1 more source

Cortical Gyrification Morphology in Neurodevelopmental and Psychiatric Disorders [PDF]

, 2022
The formation of cortical gyrification in early brain development remains a perplexing phenomenon in the field of neuroscience. The important roles of both genetic and environmental factors are evident in cortical gyrification morphology. With the aim of
Gharehgazlou, Avideh
core  

Cognitive dysfunction and cortical structural abnormalities in first-episode drug-naïve schizophrenia patients with auditory verbal hallucination

Frontiers in Psychiatry, 2022
ObjectiveThe current study aimed to examine the cognitive profiles and cortical structural alterations in first-episode drug-naïve schizophrenia with AVH (auditory verbal hallucination).MethodsCortical structural parameters including cortical thickness ...
Xuran Shen, Fuli Jiang, Xinyu Fang, Wei Yan, Shiping Xie, Rongrong Zhang   +5 more
doaj   +1 more source

Decreased gyrification in major depressive disorder

, 2008
Structural and functional abnormalities have been extensively reported in major depressive disorder, but possible changes in cortical folding have not yet been explored in this disorder.
Yu, Chunshui, Chong Lia, Zhang, Yuanchao, Jiang, Tianzi, Yuanchao Zhanga, Chunshui Yuc, Li, Kuncheng, Li, Chong, Yuan Zhoub, Tianzi Jiangb, Zhou, Yuan, Kuncheng Lic   +11 more
core   +1 more source

Decreased frontal gyrification correlates with altered connectivity in children with autism

Frontiers in Human Neuroscience, 2013
The structural correlates of functional dysconnectivity in autism spectrum disorders (ASD) have been seldom explored, despite the fact that altered functional connectivity is one of the most frequent neuropathological observations in the disorder.We ...
Marie eSchaer, Marie eSchaer, Marie-Christine eOttet, Elisa eScariati, Daniel eDukes, Daniel eDukes, Martina eFranchini, Stephan eEliez, Stephan eEliez, Bronwyn eGlaser   +9 more
doaj   +1 more source

TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains

Advanced Science, EarlyView.
Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang, Xiao Wang, Hongyan Ma, Pengcheng Lyu, Shuangjie Tian, Ruojun Zong, Jiani Chen, Gang Ren, Yongjiang Yang, Zichen Yang, Guosong Qin, Naishi Li, Yanfang Wang, Jianwei Jiao, Jianguo Zhao   +14 more
wiley   +1 more source

Cortical Thickness and Clinical Findings in Prescholar Children With Autism Spectrum Disorder

Frontiers in Neuroscience, 2022
The term autism spectrum disorder (ASD) includes a wide variability of clinical presentation, and this clinical heterogeneity seems to reflect a still unclear multifactorial etiopathogenesis, encompassing different genetic risk factors and susceptibility
Simona Lucibello, Giovanna Bertè, Tommaso Verdolotti, Martina Lucignani, Antonio Napolitano, Rosa D’Abronzo, Maria G. Cicala, Elisa Pede, Daniela Chieffo, Paolo Mariotti, Cesare Colosimo, Cesare Colosimo, Eugenio Mercuri, Eugenio Mercuri, Roberta Battini, Roberta Battini   +15 more
doaj   +1 more source

Precision Nanomedicine for Traumatic Neural Injury: Functional Paradigms and Translational Frameworks

Advanced Science, EarlyView.
This review presents a pathology‐driven framework unifying nanomedicine across TBI, SCI, and PNI. Epidemiological evidence and comparative single‐cell transcriptomic reanalysis define shared pathological modules, injury‐specific effectors, and therapeutic bottlenecks. Six functional paradigms connect nanomaterial structure and biological fate to injury‐
Mouyuan Sun, Shuangyang Li, Zhixu He, Jingyi Xie, Yaxian Luo, Xuankai Fan, Jingyu Zhang, Luying Qin, Lianjie Peng, Tao Qiu, Tian Zhang, Huiming Wang, Mengfei Yu   +12 more
wiley   +1 more source