Results 71 to 80 of about 5,830,879 (341)

HEALTHWATCH INVESTIGATIONS: Developing good practice [PDF]

, 2015
Investigating issues and concerns raised by service users, carers, patients and the wider public and getting feedback, is core business for local Healthwatch. This is an extremely challenging role.
Gamsu, M, White, JL
core  

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Sistemas de informação em saúde no nível local Health information systems at the local level

Cadernos de Saúde Pública, 1996
A importância que a informação vem assumindo na sociedade moderna transformou-a em recurso estatégico de poder em todas as áreas. É fundamental, portanto, que o processo de descentralização no setor saúde não se restrinja a ações em serviços, mas ...
Maria Alice Fernandes Branco
doaj   +1 more source

Towards Resilient Health Systems in Sub-Saharan Africa: A Systematic Review of the English Language Literature on Health Workforce, Surveillance, and Health Governance Issues for Health Systems Strengthening

Annals of Global Health, 2019
Background: Meeting health security capacity in sub-Saharan Africa will require strengthening existing health systems to prevent, detect, and respond to any threats to health.
M. Ayanore, N. Amuna, Mark A. Aviisah, Adam Awolu, D. D. Kipo-Sunyehzi, V. Mogre, R. Ofori-Asenso, J. M. Gmanyami, Nuworza Kugbey, M. Gyapong   +9 more
semanticscholar   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Understanding the Workforce Needs of New Jersey's Public Health and Other Disaster Management Employers [PDF]

, 2008
This report explores the priority workforce needs of New Jersey's public disaster management system. An advisory group of disaster management-related employers from law enforcement and state and local public health systems and educational institutions ...
Aaron Fichtner, Jennifer Cleary, Ronnie Kauder   +2 more
core  

A whole-health-economy approach to antimicrobial stewardship: Analysis of current models and future direction. [PDF]

, 2019
Antimicrobial stewardship (AMS) strategies are widely implemented in single healthcare sectors and organisations; however, the extent and impact of integrated AMS initiatives across the whole health economy are unknown. Assessing degree of integration
Ahmad, R., Holmes, A., McLeod, M., Micallef, C., Shebl, N. A., Sim, F.   +5 more
core   +5 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Towards resilient health systems: opportunities to align surgical and disaster planning

BMJ Global Health, 2019
Natural disasters significantly contribute to human death and suffering. Moreover, they exacerbate pre-existing health inequalities by imposing an additional burden on the most vulnerable populations. Robust local health systems can greatly mitigate this
Jordan S. Pyda, Rolvix H. Patterson, Luke Caddell, Taylor Wurdeman, R. Koch, D. Polatty, B. Card, J. Meara, D. S. Corlew   +8 more
semanticscholar   +1 more source