Results 71 to 80 of about 1,038,389 (257)

Promoting health through transdisciplinary local food system partnerships

Journal of Agriculture, Food Systems, and Community Development
The North Carolina Local Food Council (NCLFC) brings together leaders from diverse sectors to strengthen local and regional food systems, pro­mote equitable local food access, and drive eco­nomic growth.
Amanda Hege, Morgan Cooper, K. Alexander Soltany, Diane Beth, Maria Ramirez Perez, Alice Ammerman, Angel Cruz   +6 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Strategies for improving maternal care for ethnic minority women with obstetric anal sphincter injuries in the UK

BMC Health Services Research
Background Women from minority ethnic groups in the UK have the highest prevalence of obstetric anal sphincter injuries (OASI), including third- and fourth-degree perineal tears sustained during childbirth.
Olufisayo Olakotan, Vedhapriya Sudhakar, Jennifer Nw Lim, Mina Bhavsar, Farah Siddiqui, Rabina Ayaz, Gillian O’Brady Henry, Thillagavathie Pillay   +7 more
doaj   +1 more source

Migrant health in Italy: a better health status difficult to maintain—country of origin and assimilation effects studied from the Italian risk factor surveillance data

Population Health Metrics, 2019
Background Many studies on migrant health have focused on aspects of morbidity and mortality, but very few approach the relevant issues of migrants’ health considering behavioral risk factors.
Stefano Campostrini, Giuliano Carrozzi, Santino Severoni, Maria Masocco, Stefania Salmaso, WHO Migration Health Programme, Office of the Regional Director, WHO Regional Office for Europe, the PASSI National Coordinating group   +6 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

‘A system that is struggling’: understanding health protection resilience in England during the COVID-19 pandemic through the experiences of local health protection responders

BMC Health Services Research
Background Local health protection systems play a crucial role in infectious disease prevention and control and were critical to COVID-19 pandemic responses. Despite this vital function, few studies have explored the lived experience of health protection
Suzanne Rotheram, Stephen Clayton, Ian Buchan, Sam Ghebrehewet, Ben Barr   +4 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

[Epidemiologic surveillance in the local health system].

Revista brasileira de enfermagem, 2004
This is a qualitative study, which aims at analyzing the organization of Epidemiological Vigilance (EV) in the local health system of Feira de Santana-BA, from 1997 to 2001 > in this study the following aspects were considered: organizational structure, resources available (human and material ones), planning, execution, intra and interinstitutional and
Juliana Alves, Leite, Marluce Maria Araújo, Assis, Erenilde Marques, de Cerqueira   +2 more
openaire   +1 more source

Os Consórcios Intermunicipais de Saúde e o Sistema Único de Saúde

Cadernos de Saúde Pública
Os municípios do interior do Brasil têm enfrentado dificuldades na implementação do Sistema Único de Saúde, regulamentado na Constituição de 1988. A falta de recursos humanos e financeiros, a dificuldade de acesso a uso de tecnologias e a inexistência de
Ana Paula Gil de Lima
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