Results 81 to 90 of about 5,830,879 (341)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Serbian Health Information System (HIS) improvements 2021–2024: comparison study using stages of continuous improvement (SOCI) methodology

Health Research Policy and Systems
Background The Health Information System (HIS) in public healthcare services in Serbia was introduced in 2008, with the first comprehensive evaluation of its maturity conducted in 2021.
Bosiljka Djikanovic, Milan Kovacevic, Isidora Smigic, Marija Cvejic, Emilija Nicic, Caitlin Madevu-Matson, Steve Ollis, Vasa Curcin, Alimou Barry, Stephanie Watson-Grant   +9 more
doaj   +1 more source

Systematic, Multimethod Assessment of Adaptations Across Four Diverse Health Systems Interventions

Frontiers in Public Health, 2018
Background Many health outcomes and implementation science studies have demonstrated the importance of tailoring evidence-based care interventions to local context to improve fit.
Borsika A. Rabin, Marina S. McCreight, C. Battaglia, R. Ayele, R. Burke, P. Hess, Joseph W. Frank, R. Glasgow   +7 more
semanticscholar   +1 more source

Liquid Hydroxyurea (Xromi) for Children With Sickle Cell Anemia: A New Solution Compounding Existing Problems

Pediatric Blood &Cancer, EarlyView.
Alexandra Power‐Hays, Charles T. Quinn
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Co-designing strategies to improve advance care planning among people from culturally and linguistically diverse backgrounds with cancer: iCanCarePlan study protocol

BMC Palliative Care
Background Advance care planning (ACP) describes the process of supporting individuals at any age or stage of health to consider and share their personal values, life goals, and preferences regarding future health care. Engaging in ACP is associated with
Ashfaq Chauhan, Upma Chitkara, Ramya Walsan, Ursula M. Sansom-Daly, Elizabeth Manias, Davinia Seah, Angie Dalli, Nadine El-Kabbout, Thit Tieu, Mashreka Sarwar, Misbah Faiz, Nancy Huang, Vitor Moraes Rocha, Abhijit Pal, Reema Harrison   +14 more
doaj   +1 more source

Active Women over 50 online information and support to promote physical activity behaviour change: study protocol for a pilot trial

Pilot and Feasibility Studies, 2020
Background Physical activity has many physical and mental health benefits and can delay the development of disability in older age. However, uptake of this health behaviour is sub-optimal in women in their middle and older age.
Geraldine Wallbank, Catherine Sherrington, Leanne Hassett, Dominika Kwasnicka, Josephine Y. Chau, Fiona Martin, Philayrath Phongsavan, Anne Grunseit, Colleen Canning, Marian Baird, Roberta Shepherd, Anne Tiedemann   +11 more
doaj   +1 more source

Automatic plankton quantification using deep features [PDF]

, 2019
The study of marine plankton data is vital to monitor the health of the world’s oceans. In recent decades, automatic plankton recognition systems have proved useful to address the vast amount of data collected by specially engineered in situ digital ...
Castaño Gutiérrez, Alberto, Coz Velasco, Juan José del, Díez Peláez, Jorge, González González, Pablo, Peacock, Emily E., Sosikb, Heidi M.   +5 more
core   +2 more sources

Integrated care: learning between high-income, and low- and middle-income country health systems

Health Policy and Planning, 2017
Over the past decade, discussion of integrated care has become more widespread and prominent in both high‐ and low‐income health care systems (LMICs). The trend reflects the mismatch between an increasing burden of chronic disease and local health care ...
S. Mounier-Jack, S. Mayhew, N. Mays
semanticscholar   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source