Results 121 to 130 of about 14,847,030 (348)
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Longitudinal study of local authority child and family social workers (wave 1) Findings from a 5 year study of local authority child and family social workers in England. [PDF]
, 2019 The longitudinal study investigates recruitment, retention and career progression in local authority child and family social work over 5 years. This is the first of 5 reports.
Coburn, S +10 more
core +3 more sources
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
SYSTEMATIC POSITION OF ANTIARCHS (VERTEBRATA, PLACODERMI) FROM THE FAMENNIAN OF TVER REGION, RUSSIA
Известия высших учебных заведений: Геология и разведка, 2017 New materials of the placoderm fish Bothriolepis heckeri Luksеvics from the Famennian of the Bilovo locality (Tver Region) are studied. This species is very similar to Livnolepis zadonica (H.Obrucheva) in the structure of cranial and postcranial armours ...
S. V. Moloshnikov, V. V. Linkevich
doaj +1 more source
A Folk Tale of a Butterfly [PDF]
, 2009 This folk tale describes how a butterfly and worm respect one anotherThis collection of 77 audio files focuses on weddings and weddings speeches but also contains: folk tales, folk songs, riddles, tongue twisters, and local history from Bang smad Village
Bkra shis bzang po
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
An Interview Recalling an Argument [PDF]
, 2009 The respondent recalls an argument with a village woman.The fifty one audio and nine video files in this collection include: villages’ life stories, circle-dancing songs and performance, local history, folk tales, and interviews from Siyuewu Village ...
G.yu lha
core
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Local Government History and Localism
Policy Quarterly, 2019 The received view of state development in New Zealand is that the abolition of the ‘provincial system’ in 1876 set in motion the inexorable rise of centralised authority. The counter thesis presented in this article argues that until about 1940 central politicians, irrespective of party, were consistently engaged in empowering rather than diminishing ...
openaire +2 more sources